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Effect of thiocyanate ingestion through milk on thyroid hormone homeostasis in women

Published online by Cambridge University Press:  09 March 2007

Kishore K. Banerjee ,
P. Marimuthu ,
Piyali Bhattacharyya  and
Malay Chatterjee
Kishore K. Banerjee
Affiliation:
All India Institute of Hygiene and Public Health, 110 Chittaranjan Avenue, Calcutta 700 073, India
P. Marimuthu
Affiliation:
All India Institute of Hygiene and Public Health, 110 Chittaranjan Avenue, Calcutta 700 073, India
Piyali Bhattacharyya
Affiliation:
Division of Biochemistry, Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India
Malay Chatterjee
Affiliation:
Division of Biochemistry, Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India
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Abstract

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A thyroid-hormonal evaluation of thirty-five women consuming commercially packed milk containing thiocyanate was carried out. The mean serum thiocyanate concentration, which was measured by the FeCl3 colour test, was significantly higher (P < 0.01) than that of control subjects. Serum thyroxine (T4), triiodothyronine (T3) and thyroid-stimulating hormone (TSH) concentrations of exposed women were compared with those of thirty-five control subjects. Thiocyanate ingestion was associated with lower levels of T4 (P <0.01) and higher levels of TSH (P < 0.01) compared with the control subjects. T3 was found to be higher in the women consuming thiocyanate-containing milk but the difference was not significant. The serum T4 level was found to be negatively correlated (r −0.359, P <0.05) while the TSH level was positively correlated (r 0.354, P < 0.05) with thiocyanate concentration in the exposed group. From this study, it appears that ingestion of milk with added thiocyanate impairs thyroid function.

Keywords

MilkThiocyanateThyroid
Type
Short communcication
Information
British Journal of Nutrition , Volume 78 , Issue 5 , November 1997 , pp. 679 - 681
Copyright
Copyright © The Nutrition Society 1997

References

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