Hostname: page-component-8448b6f56d-m8qmq Total loading time: 0 Render date: 2024-04-19T10:14:55.623Z Has data issue: false hasContentIssue false
  • English
  • Français

Absorption of lycopene from single or daily portions of raw and processed tomato

Published online by Cambridge University Press:  09 March 2007

Marisa Porrini ,
Patrizia Riso  and
Giulio Testolin
Marisa Porrini*
Affiliation:
Department of Food Science and Technology, Nutrition Section, University of Milan, via Celoria 2, 20133 Milan, Italy
Patrizia Riso
Affiliation:
Department of Food Science and Technology, Nutrition Section, University of Milan, via Celoria 2, 20133 Milan, Italy
Giulio Testolin
Affiliation:
Department of Food Science and Technology, Nutrition Section, University of Milan, via Celoria 2, 20133 Milan, Italy
*
*Corresponding author: Dr Marisa Porrini, fax +39 2 7063 8625, email porrini@imiucca.csi.unimi.it
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

To study the relationship between lycopene intake and plasma concentration, ten healthy female subjects were given one or more portions of tomato purée or fresh raw tomato containing 16.5mg total lycopene (all-trans + cis forms). In Expt 1 subjects (n 9) were randomly assigned the single portions of the two tomato products and blood samples were collected to follow the change in plasma carotenoid concentrations within the first 12 h and on each of the following 5 d (104 h). In Expt 2 subjects (n 10) were divided into two groups of five each receiving daily dietary portions of tomato purée or fresh raw tomato containing 16.5mg total lycopene for 7 d. Fasting blood samples were collected daily. In Expt 1 the plasma total lycopene (all-trans + cis forms) concentration, after the single portions of tomato purée and raw tomato, varied significantly over time, with a first peak reached after 6 h, a further increase after 12 h and a slow decrease until 104 h. In Expt 2, when the tomato products were given daily, there was a day-by-day increase in the plasma total lycopene concentration, and through the following week of a diet without tomato there was a gradual decrease. However, values did not return to basal concentrations. Plasma total lycopene concentration was higher after the tomato purée intake than after the raw tomato in both the first (F (1,8) 7.597; P < 0.025) and the second experiments (F (1,8) 12.193; P < 0.01) demonstrating a significant effect of food matrix on absorption.

Keywords

AbsorptionLycopeneTomato
Type
Research Article
Information
British Journal of Nutrition , Volume 80 , Issue 4 , October 1998 , pp. 353 - 361
Copyright
Copyright © The Nutrition Society 1998

References

Ascherio, A, Stampfer, MJ, Colditz, GA, Rimm, EB, Litin, L & Willett, WC (1992) Correlations of vitamin A and E intakes with the plasma concentrations of carotenoids and tocopherols among American men and women. Journal of Nutrition 122, 1792–1801.CrossRefGoogle Scholar
Bendich, A & Olson, JA (1989) Biological actions of carotenoids. FASEB Journal 3, 1927–1932.CrossRefGoogle ScholarPubMed
Bierer, TL, Merchen, NR & Erdman, JW (1994) Comparative absorption and lipoprotein transport of five common carotenoids in the preruminant calf. FASEB Journal 8, A422 Abstr.Google Scholar
Blomstrand, R & Werner, B (1967) Studies on the intestinal absorption of radioactive β-carotene and vitamin A in man. Conversion of β-carotene into vitamin A. Scandinavian Journal of Clinical and Laboratory Investigation 19, 339–345.Google Scholar
Brown, ED, Micozzi, MS, Craft, NE, Bieri, JG, Beecher, G, Edwards, BK, Rose, A, Taylor, PR & Smith, JC (1989) Plasma carotenoids in normal men after a single ingestion of vegetables or purified β-carotene. American Journal of Clinical Nutrition 49, 1258–1265.CrossRefGoogle ScholarPubMed
Di, Mascio P, Kaiser, S & Sies, H (1989) Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Archives of Biochemistry and Biophysics 274, 532–538.Google Scholar
Dimitrov, NV, Meyer, C, Ulrey, DE, Chenowet, W, Michelakis, A, Malone, W, Boone, C & Fink, G (1988) Bioavailability of β-carotene in humans. American Journal of Clinical Nutrition 48, 298–304.CrossRefGoogle ScholarPubMed
Franceschi, F, Bidoli, E, La Vecchia, C, Talamini, R, D'Avanzo, B & Negri, E (1994) Tomatoes and risk of digestive-tract cancers. International Journal of Cancer 59, 181–184.CrossRefGoogle ScholarPubMed
Frigge, M, Hoagland, DC & Iglewicz, B (1989) Some implements of the boxplot. American Statistician 43, 50–54.CrossRefGoogle Scholar
Gerster, H (1993) Anticarcinogenic effect of common carotenoids. International Journal for Vitamin and Nutrition Research 63, 93–121.Google Scholar
Goodman, DS, Blomstrand, R, Werner, B, Huang, HS & Shiratori, T (1966) The intestinal absorption and metabolism of vitamin A and β-carotene in man. Journal of Clinical Investigation 45, 1615–1623.CrossRefGoogle ScholarPubMed
Hart, DJ & Scott, KJ (1995) Development and evaluation of an HPLC method for the analysis of carotenoids in foods, and the measurement of the carotenoid content of vegetables and fruits commonly consumed in the UK. Food Chemistry 54, 101–111.Google Scholar
Kostic, D, White, WS & Olson, JA (1995) Intestinal absorption, serum clearance, and interactions between lutein and β-carotene when administered to human adults in separate or combined oral doses. American Journal of Clinical Nutrition 62, 604–610.Google Scholar
Mathews-Roth, MM, Welankiwar, S, Sehgal, PK, Lausen, NCG, Russett, M & Krinksy, NI (1990) Distribution of [14C]canthaxanthin and [14C]lycopene in rats and monkeys. Journal of Nutrition 120, 1205–1213.CrossRefGoogle ScholarPubMed
Micozzi, MS, Brown, ED, Edwards, BK, Bieri, JG, Taylor, PR, Khachik, F, Beecher, GR & Smith, JC (1992) Plasma carotenoid response to chronic intake of selected foods and β-carotene supplements in men. American Journal of Clinical Nutrition 55, 1120–1125.CrossRefGoogle ScholarPubMed
Miller, NJ, Sampson, J, Candeias, LP, Bramley, PM & Rice-Evans, CA (1996) Antioxidant activities of carotenes and xanthophylls. FEBS Letters 384, 240–242.CrossRefGoogle ScholarPubMed
Parfitt, VJ, Rubba, P, Bolton, C, Marotta, G, Hartog, M & Mancini, M (1994) A comparison of antioxidant status and free radical peroxidation of plasma lipoproteins in healthy young persons from Naples and Bristol. European Heart Journal 15, 871–876.Google Scholar
Parker, RS (1997) Bioavailability of carotenoids. European Journal of Clinical Nutrition 51, Suppl. 1, S86–S90.Google Scholar
Porrini, M, Crovetti, R & Testolin, G (1995) Evaluation of satiety sensations and food intake after different preloads. Appetite 25, 17–30.Google Scholar
Riso, P & Porrini, M (1997) Determination of carotenoids in vegetable foods and plasma. International Journal for Vitamin and Nutrition Research 67, 47–54.Google ScholarPubMed
Rock, CL, Swendseid, ME, Jacob, RA & McKee, RW (1992) Plasma carotenoid levels in human subjects fed a low carotenoid diet. Journal of Nutrition 122, 96–100.CrossRefGoogle ScholarPubMed
Scott, KJ, Thurnham, DI, Hart, DJ, Bingham, SA & Day, K (1996) The correlation between the intake of lutein, lycopene and β-carotene from vegetables and fruits, and blood plasma concentrations in a group of women aged 50–65 years in the UK. British Journal of Nutrition 75, 409–418.Google Scholar
Stahl, W, Schwarz, W, Sundquist, AR & Sies, H (1992) Cis-trans isomers of lycopene and β-carotene in human serum and tissues. Archives of Biochemistry and Biophysics 294, 173–177.Google Scholar
Stahl, W, Schwarz, W, von Laar, J & Sies, H (1995) All-trans β-carotene preferentially accumulates in human chylomicrons and very low density lipoproteins compared with the 9-cis geometrical isomer. Journal of Nutrition 125, 2128–2133.Google Scholar
Stahl, W & Sies, H (1992) Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humans. Journal of Nutrition 122, 2161–2166.Google Scholar
Stahl, W & Sies, H (1996) Lycopene: a biologically important carotenoid for humans? Archives of Biochemistry and Biophysics 336, 1–9.CrossRefGoogle Scholar
van Vliet, T, Schreurs, WHP & van den, Berg H (1995) Intestinal β-carotene absorption and cleavage in men: response of β-carotene and retinyl esters in the triglyceride-rich lipoprotein fraction after a single oral dose of β-carotene. American Journal of Clinical Nutrition 62, 110–116.CrossRefGoogle ScholarPubMed
Willett, WC, Stampfer, MJ, Underwood, BA, Taylor, JO & Hennekens, CH (1983) Vitamins A, E, and carotene: effects of supplementation on their plasma levels. American Journal of Clinical Nutrition 38, 559–566.Google Scholar
Zhu, YI, Hsieh, W-C, Parker, RS, Herraiz, LA, Haas, JD, Swanson, JE & Roe, DA (1997) Evidence of a role for fat-free body mass in modulation of plasma carotenoid concentrations in older men: studies with hydrodensitometry. Journal of Nutrition 127, 321–326.Google ScholarPubMed