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Can host ecology and kin selection predict parasite virulence?

Published online by Cambridge University Press:  24 April 2014

ALYSSA M. GLEICHSNER  and
DENNIS J. MINCHELLA
ALYSSA M. GLEICHSNER*
Affiliation:
Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907, USA
DENNIS J. MINCHELLA
Affiliation:
Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907, USA
*
*Corresponding author: Purdue University, 915 West State Street, West Lafayette, IN 47907, USA. E-mail: agleichs@purdue.edu
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Summary

Parasite virulence, or the damage a parasite does to its host, is measured in terms of both host costs (reductions in host growth, reproduction and survival) and parasite benefits (increased transmission and parasite numbers) in the literature. Much work has shown that ecological and genetic factors can be strong selective forces in virulence evolution. This review uses kin selection theory to explore how variations in host ecological parameters impact the genetic relatedness of parasite populations and thus virulence. We provide a broad overview of virulence and population genetics studies and then draw connections to existing knowledge about natural parasite populations. The impact of host movement (transporting parasites) and host resistance (filtering parasites) on the genetic structure and virulence of parasite populations is explored, and empirical studies of these factors using Plasmodium and trematode systems are proposed.

Keywords

Virulencekin selectionparasitehost movementresistance
Type
Review Article
Information
Parasitology , Volume 141 , Issue 8 , July 2014 , pp. 1018 - 1030
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Copyright
Copyright © Cambridge University Press 2014 

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