Hostname: page-component-848d4c4894-4hhp2 Total loading time: 0 Render date: 2024-05-20T08:50:28.242Z Has data issue: false hasContentIssue false
  • English
  • Français

The effects of dietary n-3 polyunsaturated fatty acids on neutrophils

Published online by Cambridge University Press:  18 April 2008

Richard I. Sperling
Richard I. Sperling*
Affiliation:
Department of Medicine, Haward Medical School, Division of Rheumatology and Immunology, Brigham & Women's Hospital, Boston, MA 02115, USA
*
Corresponding author: Dr R. I. Sperling, fax +1 508 822 7975
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Meeting Report
Information
Proceedings of the Nutrition Society , Volume 57 , Issue 4 , November 1998 , pp. 527 - 534
Copyright
Copyright © The Nutrition Society 1998

Footnotes

*

Health Associates of Taunton, Cutter Place, 152 Dean Street, Taunton, MA 02780, USA.

References

Astorga, GP, Cubillos, AC, Masson, LS & Silva, JJS (1991) Artritis rehumatoidea activa: Efecto de la suplementacion dietetica con aceites omega-3. Estudio doble-ciego controlado (Active rheu- matoid arthritis: the effect of dietary supplementation with w-3 oils. A double-blind, controlled study). Revista Medica De Chile 119, 267–272.Google Scholar
Borenstein, DG & Vanderhoek, JY (1987) Arthritis and Rheumatism 30, 565 Abstr.Google Scholar
Borgeat, P & Samuelsson, B (1979) Arachidonic acid metabolism in polymorphonucleocytes: Effects of ionophore A23187. Proceedings of the National Academy of Sciences USA 76, 2148–2152.CrossRefGoogle Scholar
Chalmers, TC, Smith, H Jr & Blackbum, B (1981) A method for assessing the quality of a randomized control trial. Controlled Clinical Trials 2, 3149.CrossRefGoogle ScholarPubMed
Cleland, LG, French, JK, Betts, WH, Murphy, G & Elliott, MJ (1988) Clinical and biochemical effects of dietary fish oil supplements in rheumatoid arthritis. Journal of Rheumatology 15, 1471–1475.Google ScholarPubMed
DerSimonian, R & Laird, N (1986) Meta-analysis in clinical trials. Controlled Clinical Trials 7, 177–188.CrossRefGoogle ScholarPubMed
Fels, AO, Pawlowski, NA, Cramer, EB, King, TKC, Cohn, ZA & Scott, WA (1982) Human alveolar macrophages produce LTB4. Proceedings of the National Academy of Sciences USA 79, 7866–7870.CrossRefGoogle Scholar
Fitzpatrick, F, Haeggström, J, Granström, E & Samuelsson, B (1983) Metabolism of LTA4 by an enzyme in blood plasma: A possible leukotactic mechanism. Proceedings of the National Academy of Sciences USA 80, 5425–5429.CrossRefGoogle ScholarPubMed
Fitzpatrick, F, Liggett, W, McGee, J, Bunting, S, Morton, D & Samuelsson, B (1984) Metabolism of LTA4 by human erythrocytes. A novel cellular source of leukotriene B4. Journal of Biological Chemistry 259, 11403–11407.CrossRefGoogle ScholarPubMed
Fortin, PF, Lew, RA, Liang, MH, Wright, EA, Beckett, LA, Chalmers, T & Sperling, RI (1995) Validation of a metaanalysis: The effects of fish oil in rheumatoid arthritis. Journal of Clinical Epidemiology 48, 1379–1390.CrossRefGoogle ScholarPubMed
Godard, P, Damon, M, Michel, FB, Corey, EJ, Austen, K & Lewis, RA (1983) LTB4 production from human alveolar macrophages. Clinical Research 31, 548A.Google Scholar
Goetzl, E & Pickett, W (1980) The human PMN leukocyte chemotactic activity of complex hydroxyeicosatetraenoic acids (HETEs). Journal of Immunology 125, 1789–1791.CrossRefGoogle Scholar
Hoover, RL, Karnovsky, MJ, Austen, KF, Corey, E & Lewis, RA (1984) LTB4 action on endothelium mediates augmented neutrophil/endothelial adhesion. Proceedings of the National Academy of Sciences USA 81, 2191–2193.CrossRefGoogle ScholarPubMed
Kjeldsen-Kragh, J, Lund, JA, Tove, R, Finnanger, B, Haaland, K, Finstad, R, Mikkelsen, K & Førre, Ø (1992) Dietary omega-3 fatty acid supplementation and naproxen treatment in patients with rheumatoid arthritis. Journal of Rheumatology 19, 1531–1536.Google ScholarPubMed
Klickstein, LB, Shapleigh, C & Goetzl, EJ (1980) Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis. Journal of Clinical Investigation 66, 1166–1170.CrossRefGoogle ScholarPubMed
Kragballe, K, Voorhees, JJ & Goetzl, EJ (1987) Inhibition by leukotriene B5 of leukotriene B4-induced activation of human keratinocytes and neutrophils. Journal of Investigative Dematology 88, 555–558.CrossRefGoogle ScholarPubMed
Kremer, JM, Bigauoette, J, Michalek, AV, Lininger, L, Huyck, C, Timchalk, MA, Rynes, RI, Zieminski, K & Bartholomew, LE (1985) Effects of manipulation of dietary fatty acids on clinical manifestation of rheumatoid arthritis. Lancet i, 184–187.CrossRefGoogle Scholar
Kremer, JM, Jubiz, W, Michalek, A, Rynes, RI, Bartholomew, LE, Bigauoette, J, Timchalk, M, Beeler, D & Lininger, L (1987) Fish oil fatty acid supplementation in active rheumatoid arthritis. Annals of Internal Medicine 106, 497–503.CrossRefGoogle ScholarPubMed
Kremer, JM, Lawrence, DA, Jubiz, W, Digiacomo, R, Rynes, R, Bartholomew, LE & Sherman, M (1990) Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis: Clinical and immunologic effects. Arthritis and Rheumatism 33, 810–820.CrossRefGoogle ScholarPubMed
Lee, TH, Hoover, RL, Williams, JD, Sperling, RI, Ravalese, JR III, Spur, BW, Robinson, DR, Corey, EJ, Lewis, RA & Austen, KF (1985) Effect of dietary supplementation with eicosapentaenoic acid and docosahexaenoic acid on in vitro neutrophil and monocyte leukotriene generation and neutrophil function. New England Journal of Medicine 312, 1217–1223.CrossRefGoogle Scholar
Lee, TH, Mencia-Huerta, J-M, Shih, C, Corey, EJ & Austen, KF (1984 a) Characterization and biological properties of 5,12- dihydroxy derivatives of EPA, including LTB5 and the double lipoxygenase product. Journal of Biological Chemistry 259, 2383–2389.CrossRefGoogle Scholar
Lee, TH, Mencia-Huerta, J-M, Shih, C, Corey, EJ, Lewis, RA & Austen, KF (1984 b) Effects of exogenous arachidonic acid, eicosapentaenoic acid and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore activated human neutrophils. Journal of Clinical Investigation 74, 1922–1933.CrossRefGoogle ScholarPubMed
Leventhal, LJ, Boyce, EG & Zurier, RB (1993) Treatment of rheumatoid arthritis with gammalinolenic acid. Annals of Internal Medicine 119, 867–873.CrossRefGoogle ScholarPubMed
Leventhal, LJ, Boyce, EG & Zurier, RB (1994) Treatment of rheumatoid arthritis with blackcurrant seed oil. British Journal of Rheumatology 33, 847–852.CrossRefGoogle ScholarPubMed
Nathaniel, DJ, Evans, JF, Leblanc, Y, Leveille, C, Fitzsimmons, BJ & Ford-Hutchinson, AW (1985) LTA5 is a substrate and an inhibitor of rat and human LT& hydrolase. Biochemical and Biophysical Research Communications 131, 827–835.CrossRefGoogle Scholar
Nielsen, GL, Faarvang, KL, Thomsen, BS, Teglbjaerg, KL, Jensen, LP, Hansen, TM, Lerbang, HH, Schmidt, EB, Dyerberg, J & Ernst, E (1992) The effects of dietary supplementation with n-3 polyunsaturated fdtty acids in patients with rheumatoid arthritis: A randomized, double blind trial. European Journal of Clinical Investigation 22, 687–691.CrossRefGoogle ScholarPubMed
Palmer, RMJ, Stephaney, RJ, Higgs, GA & Eakins, KE (1980) Chemokinetic activity of arachidonic acid lipoxygenase products on leukocytes of different species. Prostaglandins 20, 411–418.CrossRefGoogle ScholarPubMed
Prescott, SM, Zimmerman, GA & Morrson, AR (1985) The effects of a diet rich in fish oil on human neutrophils: Identification of leukotriene B5 as a metabolite. Prostaglandins 30, 209–227.CrossRefGoogle Scholar
Pullman-Mooar, S, Laposata, M, Lem, D, Holman, RT, Leventhal, LJ, DeMarco, D & Zurier, RB (1990) Alteration of the cellular fatty acid profile and the production of eicosanoids in human monocytes by gamma-linolenic acid. Arthritis and Rheumatism 33, 1526–1533.CrossRefGoogle ScholarPubMed
Rådmark, O, Shimizu, T, Jørnvall, H & Samuelsson, B (1984) LTA4 hydrolase in human leukocytes. Journal of Biological Chemistry 259, 12339–12345.CrossRefGoogle ScholarPubMed
Robinson, DR (1988) Rheumatoid arthritis. In Primer on the Rheumatic Diseases, 9th ed., pp. 24–30 [Schumacher, HR, Klipple, JH and Robinson, DR, editors]. Atlanta, GA: Arthritis Foundation.Google Scholar
Rossetti, RG, Seiler, CM, DeLuca, P, Laposata, M & Zurier, RB (1997) Oral administration of unsaturated fatty acids: Effects on human peripheral blood T lymphocyte proliferation. Journal of Leukocyte Biology 62, 438–443.CrossRefGoogle ScholarPubMed
Rouzer, CA, Matsumoto, T & Samuelsson, B (1986) Single protein from human leukocytes possesses 5-lipoxygenase and LTA4 synthetase activities. Proceedings of the National Academy of Sciences USA 83, 857–861.CrossRefGoogle Scholar
Shak, S & Goldstein, IM (1985) Leukotriene B4 whydroxylase in human polymorphonuclear leukocytes. Journal of Clinical Investigation 76, 1218–1228.CrossRefGoogle Scholar
Soberman, RJ, Harper, RW, Murphy, RC & Austen, KF (1985) Identification and functional characterization of leukotriene B4 hydroxylase in human polymorphonuclear leukocytes. Proceedings of the National Academy of Sciences USA 82, 2292–2295.CrossRefGoogle ScholarPubMed
Sperling, RI, Benincaso, AI, Knoelle, C, Austen, KF & Robinson, DR (1993 a) Dietary ω-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. Journal of Clinical Investigation 91, 651–460.CrossRefGoogle ScholarPubMed
Sperling, RI, Sohl, P, Chen, ZS, Lewis-Mannion, M, Austen, KF & Robinson, DR (1993 b) Suppressed chemotactic responsiveness of PMN from patients with RA is due to downregulated receptor number and signaling. Arthritis and Rheumatism 36, S244 Abstr.Google Scholar
Sperling, RI, Weinblatt, M, Robin, J-L, Ravalese, JR III, Spur, BW, Robinson, DR, Corey, EJ, Lewis, RA & Austen, KF (1987) Effects of dietary supplementation with marine fish oil on leukocyte lipid mediator generation and function in rheumatoid arthritis. Arthritis and Rheumatism 30, 988–997.CrossRefGoogle ScholarPubMed
Strasser, T, Fischer, S & Weber, PC (1985) Leukotriene B5 is formed in human neutrophils after dietary supplementation with eicosapentaenoic acid. Proceedings of the National Academy of Sciences USA 82, 1540–1543.CrossRefGoogle Scholar
Terano, T, Seya, A, Harai, A, Saito, H, Tamura, Y & Yoshida, S (1987) Effect of oral administration of highly purified EPA and DHA on eicosanoid formation and neutrophil function in healthy subjects. In Proceedings of the AOCS Short Course on: Polyunsaiurated Fatty Acids and Eicosanoids, pp. 133–138 [Lands, WEM, editor]. Champaign, IL: American Oil Chemists' Society.Google Scholar
Tulleken, JE, Limburg, PC, Muskiet, FAJ & van Rijswijk, MH (1990) Vitamin E status during dietary fish oil supplementation in rheumatoid arthritis. Arthritis and Rheumatism 33, 1416–1419.CrossRefGoogle ScholarPubMed
van der Temple, H, Tulleken, JE, Limburg, PC, Muskiet, FAJ & van Rijswijk, MH (1990) Effects of fish oil supplementation in rheumatoid arthritis. Annals of the Rheumatic Diseases 49, 76–80.CrossRefGoogle Scholar
Williams, JD, Czop, JK & Austen, KF (1984) Release of leukotrienes by human monocytes on Effect of oral administration of highly purified epa anstimulation of their phagocytic receptor for particulate activators. Journal of Immunology 132, 3034–3040.CrossRefGoogle Scholar
Yasaka, T, Boxer, LA & Baehner, RL (1982) Monocyte aggregation and superoxide anion release in response to formyl-methionyl-leucyl-phenylalanine (FMLP) and platelet-activating factor (PAF). Journal of Immunology 128, 1939–1944.CrossRefGoogle ScholarPubMed
Ziboh, VA & Fletcher, MP (1992) Dose-response effects of dietary-γ-linolenic acid-enriched oils on human polymorphonuclearneutrophil biosynthesis of leukotriene B4. American Journal of Clinical Nuirition 55, 39–45.CrossRefGoogle ScholarPubMed
Zurier, RB, Rossetti, RG, Jacobson, EW, DeMarco, DM, Liu, NY, Temming, E, White, BM & Laposata, M (1996) Gamma- linolenic acid treatment of rheumatoid arthritis: A randomized, placebocontrolled trial. Arthritis and Rheumatism 39, 1808–1817.CrossRefGoogle Scholar