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Multicore Myopathy: Not Always a Benign Entity

Published online by Cambridge University Press:  18 September 2015

Ashfaq Shuaib ,
Justin M.E. Martin ,
L. Brent Mitchell  and
A. Keith W. Brownell
Ashfaq Shuaib
Affiliation:
Department of Clinical Neurosciences, The Faculty of Medicine, University of Calgary, Calgary
Justin M.E. Martin
Affiliation:
Department of Histopathology, The Faculty of Medicine, University of Calgary, Calgary
L. Brent Mitchell
Affiliation:
Department of Medicine, The Faculty of Medicine, University of Calgary, Calgary
A. Keith W. Brownell*
Affiliation:
Department of Clinical Neurosciences, The Faculty of Medicine, University of Calgary, Calgary Department of Medicine, The Faculty of Medicine, University of Calgary, Calgary
*
Department of Clinical Neurosciences, The University of Calgary, Foothills Hospital, 1403 29th St. N.W., Calgary, Alberta, Canada T2N 2T9
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Abstract:

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Four patients with Multicore Myopathy, a rare morphologically distinct myopathy, are described. Although previously considered to be a non-progressive or only slowly progressive myopathy, progression to significant disability was seen in three of our cases. The association of cardiac disease with Multicore Myopathy has not been previously emphasised. All four patients in this study had a cardiomyopathy, and heart disease was the cause of death in two of the patients. Multicore Myopathy is not always a benign entity. Cardiac involvement, when present, adversely affects prognosis.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 15 , Issue 1 , February 1988 , pp. 10 - 14
Copyright
Copyright © Canadian Neurological Sciences Federation 1988

References

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