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Cool and hot executive function in conduct-disordered adolescents with and without co-morbid attention deficit hyperactivity disorder: relationships with externalizing behaviours

Published online by Cambridge University Press:  30 January 2013

M. Dolan*
Affiliation:
Centre for Forensic Behavioural Science, Monash University, Victoria, Australia The Victorian Institute of Forensic Mental Health, Melbourne, Australia
C. Lennox
Affiliation:
The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
*
*Address for correspondence: Professor M. Dolan, Centre for Forensic Behavioural Science, Monash University, 505 Hoddle Street, Clifton Hill, VIC 3068, Australia. (Email: mairead.dolan@forensicare.vic.gov.au)

Abstract

Background

An understanding of the exact nature of executive function (EF) deficits in conduct disorder (CD) remains elusive because of issues of co-morbidity with attention deficit hyperactivity disorder (ADHD).

Method

Seventy-two adolescents with CD, 35 with CD + ADHD and 20 healthy controls (HCs) were assessed on a computerized battery of putative ‘cool’ and ‘hot’ EFs. Participants also completed the Child Behaviour Checklist (CBCL).

Results

In the cool EF tasks such as planning, the CD + ADHD group in particular showed most notable impairments compared to HCs. This pattern was less evident for set shifting and behavioural inhibition but there were significant correlations between errors scores on these tasks and indices of externalizing behaviours on the CBCL across the sample. For hot EF tasks, all clinical groups performed worse than HCs on delay of gratification and poor performance was correlated with externalizing scores. Although there were no notable group differences on the punishment-based card-playing task, there were significant correlations between ultimate payout and externalizing behaviour across groups.

Conclusions

Overall, our findings highlight the fact that there may be more common than distinguishing neuropsychological underpinnings to these co-morbid disorders and that a dimensional symptom-based approach may be the way forward.

Type
Original Articles
Copyright
Copyright © Cambridge University Press 2013 

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References

Achenbach, TM (1991). Manual for the Child Behavior Checklist/4–18 and 1991 Profile. Department of Psychiatry, University of Vermont: Burlington, VT.Google Scholar
Ackerman, PT, Anhalt, JM, Dykman, RA (1986). Arithmetic automatization failure in children with attention and reading disorders: associations and sequela. Journal of Learning Disabilities 19, 222232.CrossRefGoogle ScholarPubMed
Arffa, S, Lovell, M, Podell, K, Goldberg, E (1998). Wisconsin Card Sorting Test performance in above average and superior school children: relationship to intelligence and age. Archives of Clinical Neuropsychology 13, 713720.Google ScholarPubMed
Barkley, RA (1998). Attention-Deficit Hyperactivity Disorder, 2nd edn. Guilford Press: New York.CrossRefGoogle ScholarPubMed
Barkley, RA, Edwards, G, Laneri, M, Fletcher, K, Metevia, L (2001). Executive functioning, temporal discounting, and sense of time in adolescents with attention deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Journal of Abnormal Child Psychology 29, 541556.CrossRefGoogle ScholarPubMed
Barnett, R, Maruff, P, Vance, A, McStephen, M, Costin, J, Luk, E (2009). Neurocognitive function in ADHD with and without comorbid disruptive behaviour disorders. Australian and New Zealand Journal of Psychiatry 43, 722730.CrossRefGoogle ScholarPubMed
Bechara, A, Damsio, H, Tranel, D, Demasio, AR (1997). Deciding advantageously before knowing the advantageous strategy. Science 275, 12931295.CrossRefGoogle ScholarPubMed
Biederman, J, Petty, CR, Clarke, A, Lomedico, A, Farone, SV (2011). Predictors of persistent ADHD: an 11-year follow-up study. Journal of Psychiatric Research 45, 150155.CrossRefGoogle ScholarPubMed
Clarke, C, Prior, M, Kinsella, GJ (2000). Do executive function deficits differentiate between adolescents with ADHD and oppositional defiant/conduct disorder? A neuropsychological study using the Six Elements test and Hayling Sentence Completion test. Journal of Abnormal Child Psychology 28, 402414.Google Scholar
DeVito, EE, Blackwell, AD, Kent, L, Ersche, KD, Clark, L, Salmond, CH, Dezsery, AM, Sahakian, BJ (2008). The effects of methylphenidate on decision making in attention deficit hyperactivity disorder. Biological Psychiatry 64, 636639.CrossRefGoogle ScholarPubMed
Dolan, M (2012). The neuropsychology of prefrontal function in antisocial personality disordered offenders with varying degrees of psychopathy. Psychological Medicine 42, 17151725.CrossRefGoogle ScholarPubMed
Dolan, M, Park, I (2002). The neuropsychology of antisocial personality disorder. Psychological Medicine 32, 417427.CrossRefGoogle ScholarPubMed
Farrington, DP (1989). Early predictors of adolescent aggression and adult violence. Violence and Victims 4, 79101.CrossRefGoogle ScholarPubMed
Fray, PJ, Robbins, TW, Sahakian, BJ (1997). Neuropsychiatric applications of CANTAB. International Journal of Geriatric Psychiatry 11, 329336.3.0.CO;2-6>CrossRefGoogle Scholar
Geurts, HM, Verté, S, Oosterlaan, J, Roeyers, H, Sergeant, JA (2004). How specific are executive functioning deficits in attention deficit hyperactivity disorders and autism? Journal of Child Psychology and Psychiatry and Allied Disciplines 45, 836854.CrossRefGoogle ScholarPubMed
Harrier, LK, DeOrnellas, K (2005). Performance of children diagnosed with ADHD on selected planning and reconstitution tests. Applied Neuropsychology 12, 106119.CrossRefGoogle ScholarPubMed
Heaton, RK (1981). A Manual for the Wisconsin Card Sorting Test. Psychological Assessment Resources: Odessa, FL.Google Scholar
Hobson, CW, Scott, S, Rubia, K (2011). Investigation of cool and hot executive function in ODD/CD independently of ADHD. Journal of Child Psychology and Psychiatry 52, 10351043.CrossRefGoogle ScholarPubMed
Hummer, TA, Kronenberger, WG, Wang, Y, Dunn, D, Mosier, KM, Kalnin, AJ, Mathews, VP (2011). Executive functioning characteristics associated with ADHD comorbidity in adolescents with disruptive behavior disorders. Journal of Abnormal Child Psychology 39, 1119.CrossRefGoogle ScholarPubMed
Hurt, J, Naglieri, JA (1992). Performance of delinquent and nondelinquent males on planning, attention, simultaneous, and successive cognitive processing tasks. Journal of Clinical Psychology 48, 120128.3.0.CO;2-5>CrossRefGoogle ScholarPubMed
Jensen, PS, Hinshaw, SP, Kraemer, HC, Lenora, N, Newcorn, JH, Abikoff, HB, March, JS, Arnold, LE, Cantwell, DP, Conners, CK, Elliott, GR, Greenhill, LL, Hechtman, L, Hoza, B, Pelham, WE, Severe, JB, Swanson, JM, Wells, KC, Wigal, T, Vitiello, B (2001). ADHD comorbidity findings from the MTA study: comparing comorbid subgroups. Journal of the American Academy of Child and Adolescent Psychiatry 40, 147158.CrossRefGoogle ScholarPubMed
Kaufman, J, Birmaher, B, Brent, D, Rao, U, Ryan, N (1996). Schedule for Affective Disorders and Schizophrenia in School-Age Children – Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. Journal of the Academy of Child and Adolescent Psychiatry 36, 980998.CrossRefGoogle Scholar
Lahey, BB, Loeber, R, Burke, JD, Applegate, B (2005). Predicting future antisocial personality disorder in males from a clinical assessment in childhood. Journal of Consulting and Clinical Psychology 73, 389399.CrossRefGoogle ScholarPubMed
Luegar, RJ, Gill, KJ (1990). Frontal-lobe cognitive dysfunction in conduct disorder adolescents. Journal of Clinical Psychology 46, 696706.3.0.CO;2-#>CrossRefGoogle Scholar
Mahone, EM, Hagelthorn, KM, Cutting, LE, Schuerholz, LJ, Pelletier, SF, Rawlins, C, Singer, HS, Denckla, MB (2002). Effects of IQ on executive function measures in children with ADHD. Child Neuropsychology 8, 5265.CrossRefGoogle ScholarPubMed
Martinussen, R, Hayden, J, Hogg-Johnson, S, Tannock, R (2005). A meta-analysis of working memory impairments in children with attention-deficit/hyperactivity disorder. Journal of the Academy of Child and Adolescent Psychiatry 44, 337384.CrossRefGoogle ScholarPubMed
Moffitt, TE, Henry, B (1991). Neuropsychological studies of juvenile delinquency and violence: a review. In Neuropsychology of Aggression (ed. Miller, J. S.), pp. 6791. Kluwer Academic Publishers: Norwell, MA.CrossRefGoogle Scholar
Morgan, AB, Lilienfeld, SO (2000). A meta-analytic review of the relation between antisocial behavior and neuropsychological measures of executive function. Clinical Psychology Review 20, 113136.CrossRefGoogle ScholarPubMed
Murphy, KR, Barkley, R, Bush, T (2001). Executive functioning and olfactory identification in young adults with attention deficit hyperactivity disorder. Neuropsychology 15, 211220.CrossRefGoogle ScholarPubMed
Newman, JP, Kosson, DS, Patterson, CM (1992). Delay of gratification in psychopathic and nonpsychopathic offenders. Journal of Abnormal Psychology 101, 630636.CrossRefGoogle ScholarPubMed
Newman, JP, Patterson, CM, Kosson, DS (1987). Response perseveration in psychopaths. Journal of Abnormal Psychology 96, 145148.CrossRefGoogle ScholarPubMed
Nigg, JT, Carte, ET, Hinshaw, SP, Treuting, JJ (1998). Neuropsychological correlates of childhood attention deficit hyperactivity disorder: explainable by comorbid disruptive behaviour or reading problems? Journal of Abnormal Psychology 107, 468480.CrossRefGoogle ScholarPubMed
Oosterlaan, J, Scheres, A, Sergeant, JA (2005). Which executive functioning deficits are associated with AD/HD, ODD/CD and comorbid AD/HD + ODD/CD? Journal of Abnormal Child Psychology 33, 6985.CrossRefGoogle ScholarPubMed
Oosterlaan, J, Sergeant, JA (1998). Response inhibition and response re-engagement in attention-deficit-hyperactivity disorder, disruptive, anxious and normal children. Behavioral Brain Research 94, 3343.CrossRefGoogle ScholarPubMed
Owen, AM, Downes, JJ, Sahakian, BJ, Polkey, CE, Robbins, TW (1990). Planning and spatial working memory following frontal lobe lesions in man. Neuropsychologia 28, 10211034.CrossRefGoogle ScholarPubMed
Pennington, BF, Ozonoff, S (1996). Executive functions and developmental psychopathology. Journal of Child Psychology and Psychiatry 37, 5187.CrossRefGoogle ScholarPubMed
Rogers, RD, Blackshaw, AJ, Middleton, HC, Matthews, K, Hawtin, K, Crowley, C, Hopwood, A, Wallace, C, Deakin, JFW, Sahakian, BJ, Robbins, TW (1999). Tryptophan depletion impairs stimulus-reward learning while methylphenidate disrupts attentional control in healthy young adults: implications for the monoaminergic basis of impulsive behaviour. Psychopharmacology 146, 482491.CrossRefGoogle ScholarPubMed
Roiser, JP, Rubinstein, JS, Sahakian, BJ (2003). Cognition in depression. Psychiatry 2, 4347.Google Scholar
Rubia, K (2011). ‘Cool’ inferior frontostriatal dysfunction in attention-deficit/hyperactivity disorder versus ‘hot’ ventromedial orbitofrontal-limbic dysfunction in conduct disorder: a review. Biological Psychiatry 69, 6987.CrossRefGoogle ScholarPubMed
Rubia, K, Russell, T, Overmeyer, S, Brammer, MJ, Bullmore, ET, Sharma, T, Simmons, A, Williams, SCR, Giampietro, V, Andrew, CM, Taylor, E (2001). Mapping motor inhibition: conjunctive brain activation across different versions of Go/NoGo and Stop tasks. NeuroImage 13, 250261.CrossRefGoogle Scholar
Rubia, K, Smith, A, Taylor, E, Brammer, M (2007). Temporal lobe dysfunction in medication-naïve boys with attention deficit/hyperactivity disorder during attention allocation. Biological Psychiatry 62, 9991006.CrossRefGoogle ScholarPubMed
Sahakian, BJ, Morein-Zamir, S (2011). Depression and resilience: insights from cognitive, neuroimaging and psychopharmacological studies. In Decision Making, Affect, and Learning: Attention and Performance XX111. (ed. Delgado, M. R., Phelps, E. A. and Robbins, T. W.), pp. 505532. Oxford University Press: New York.CrossRefGoogle Scholar
Sarkis, SM, Sarkis, EH, Marshall, D, Archer, J (2005). Self-regulation and inhibition in comorbid ADHD children: an evaluation of executive functions. Journal of Attention Disorders 8, 96108.CrossRefGoogle ScholarPubMed
Schacher, R, Logan, GD (1990). Impulsivity and inhibitory control in normal development and childhood psychopathology. Developmental Psychology 26, 710720.CrossRefGoogle Scholar
Seguin, JR, Pihl, RO, Harden, PW, Tremblay, RE, Boulerice, B (1995). Cognitive and neuropsychological characteristics of physically aggressive boys. Journal of Abnormal Psychology 104, 614624.CrossRefGoogle ScholarPubMed
Seidman, LJ, Biederman, J, Monuteaux, MC, Doyle, A, Faraone, SV (2001). Learning disabilities and executive dysfunction in boys with attention-deficit/hyperactivity disorder. Neuropsychology 15, 544556.CrossRefGoogle ScholarPubMed
Siegel, RA (1978). Probability of punishment and suppression of behavior in psychopathic and nonpsychopathic offenders. Journal of Abnormal Psychology 87, 514522.CrossRefGoogle ScholarPubMed
Thapar, A, Harrington, R, McGuffin, P (2001). Examining the comorbidity of ADHD related behaviours and conduct problems using a twin study design. British Journal of Psychiatry 179, 224229.CrossRefGoogle ScholarPubMed
Toplak, ME, Jain, U, Tannock, R (2005). Decision-making and cognitive abilities in adolescents with Attention-Deficit-Hyperactivity Disorder (ADHD). Behavioral and Brain Functions 1, 8.CrossRefGoogle Scholar
Toupin, J, Déry, M, Pauzé, R, Mercier, H, Fortin, L (2000). Cognitive and familial contributions to conduct disorder in children. Journal of Child Psychology and Psychiatry 41, 333344.CrossRefGoogle ScholarPubMed
Vance, A, Maruff, P, Barnett, R (2003). Attention deficit hyperactivity disorder, combined type (ADHD-CT): better executive function performance with longer-term psychostimulant medication. Australian and New Zealand Journal of Psychiatry 37, 570576.CrossRefGoogle ScholarPubMed
van Goozen, SH, Cohen-Kettenis, PT, Snoek, H, Matthys, W, Swaab-Barneveld, H, van Engeland, H (2004). Executive functioning in children: a comparison of hospitalised ODD and ODD/ADHD children and normal controls. Journal of Child Psychology and Psychiatry 45, 284292.CrossRefGoogle ScholarPubMed
Vitelli, R (1998). Childhood disruptive disorders and adults psychopathy. American Journal of Forensic Psychology 16, 2937.Google Scholar
Wechsler, D (1999). Wechsler Abbreviated Scale of Intelligence. The Psychological Corporation: San Antonio, TX.Google Scholar
Willcutt, EG, Doyle, AE, Nigg, JT, Faraone, SV, Pennington, BF (2005). Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biological Psychiatry 57, 13361346.CrossRefGoogle ScholarPubMed