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PREVALENCE OF CONSANGUINEOUS MARRIAGES AMONG IRANIAN GEORGIANS

Published online by Cambridge University Press:  28 June 2010

LALEH RAFIEE
Affiliation:
Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran
MOSTAFA SAADAT
Affiliation:
Department of Biology, College of Sciences, Shiraz University, Shiraz, Iran

Summary

Consanguineous marriage – marriage between relatives – has received a great deal of attention as a potential risk factor for many adverse health outcomes. The present cross-sectional study was done in order to illustrate the prevalence and types of consanguineous marriages among Iranian Georgians living in Frydoonshahr (Isfahan province, central Iran). Data on consanguineous marriages were collected using a simple questionnaire. The total number of couples in this study was 646. Consanguineous marriage was classified by the degree of relationship between couples. First cousin marriages (14.2%) were the most common type of consanguineous marriages, followed by second cousin (7.0%), beyond second cousin (1.5%) and first cousin once removed (0.6%). The mean inbreeding coefficient (α) was calculated as 0.0104 for the population. The present study shows that the study population, as other Iranian populations, has a high level of consanguinity.

Type
Research Article
Copyright
Copyright © Cambridge University Press 2010

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References

Akrami, S. M., Montazeri, V., Shomali, S. R., Heshmat, R. & Larijani, B. (2009) Is there a significant trend in prevalence of consanguineous marriage in Tehran? A review of three generations. Journal of Genetic Counseling 18, 8286.Google Scholar
Akrami, S. M. & Osati, Z. (2007) Is consanguineous marriage religiously encouraged? Islamic and Iranian considerations. Journal of Biosocial Science 39, 313316.Google Scholar
Amirshahi, P., Sunderland, E., Farhud, D. D., Tavakoli, S. H. & Daneshmand, P. (1989) Serum proteins and erythrocyte enzymes of populations in Iran. Human Heredity 39, 7580.Google Scholar
Bittles, A. H. (2001) Consanguinity and its relevance to clinical genetics. Clinical Genetics 60, 8998.CrossRefGoogle ScholarPubMed
Bittles, A. H. (2003) The bases of western attitudes to consanguineous marriage. Developmental Medicine and Child Neurology 45, 135138.Google Scholar
Bittles, A. H., Grant, J. C. & Shami, S. A. (1993) An evaluation of consanguinity as a determinant of reproductive behaviour and mortality in Pakistan. International Journal of Epidemiology 22, 463467.Google Scholar
Farhud, D. D., Mahmoudi, M., Kamali, M. S., Andonian, L. & Saffari, R. (1991) Consanguinity in Iran. Iranian Journal of Public Health 20, 116.Google Scholar
Hafez, M., El-Tahan, H., Awadalla, M., El-Khayat, H., Abdel-Gafar, A. & Ghoneim, M. (1983) Consanguineous matings in the Egyptian population. Journal of Medical Genetics 20, 5860.Google Scholar
Hamamy, H., Jamhawi, L., Al-Darawsheh, J. & Ajlouni, K. (2005) Consanguineous marriages in Jordan: why is the rate changing with time? Clinical Genetics 67, 511516.CrossRefGoogle ScholarPubMed
Kamkar, M., Saadat, M., Saadat, I. & Haghighi, G. (2003) Report of VNTR with 13 repeats linked to phenylalanine hydroxylase locus in unrelated members of two PKU families. Iranian Biomedical Journal 7, 8990.Google Scholar
Mohamadynejad, P. & Saadat, M. (2008) Genetic polymorphisms of XRCC1 (at codons 194 and 399) in Shiraz population (Fars province, southern Iran). Molecular Biology Reports 35, 669672.Google Scholar
Nafissi, S., Ansari-Lari, M. & Saadat, M. (2010) Effect of inbreeding on weight gain of offspring from birth to 12 months after birth: a study from Iran. Journal of Biosocial Science 42, 195200.CrossRefGoogle ScholarPubMed
Othman, H. & Saadat, M. (2009) Prevalence of consanguineous marriages in Syria. Journal of Biosocial Science 41, 685692.CrossRefGoogle ScholarPubMed
Rafeei, L., Saadat, I. & Saadat, M. (2009) Glutathione S-transferase genetic polymorphisms (GSTM1, GSTT1 and GSTO2) in three Iranian populations. Molecular Biology Reports 37, 155158.CrossRefGoogle Scholar
Saadat, M. (2005) Epidemiology and mortality of hospitalized burn patients in Kohkiluye va Boyerahmad province (Iran): 2002–2004. Burns 31, 306309.Google Scholar
Saadat, M. (2007) Consanguineous marriages in Iranian folktales. Community Genetics 10, 3740.Google ScholarPubMed
Saadat, M. (2008a) Consanguinity and national IQ. Journal of Epidemiology and Community Health 62, 566567.Google Scholar
Saadat, M. (2008b) Is consanguineous marriage historically encouraged? Journal of Biosocial Science 40, 153154.CrossRefGoogle ScholarPubMed
Saadat, M., Ansari-Lari, M. & Farhud, D. D. (2004) Consanguineous marriage in Iran. Annals of Human Biology 31, 263269.CrossRefGoogle ScholarPubMed
Saadat, M. & Zendeh-Boodi, Z. (2006) Correlation between incidences of self-inflicted burns and means of inbreeding coefficients: an ecological study. Annals of Epidemiology 16, 708711.CrossRefGoogle Scholar
Stoltenberg, C., Magnus, P., Skrondal, A. & Lie, R. T. (1999) Consanguinity and recurrence risk of stillbirth and infant death. American Journal of Public Health 89, 517523.Google Scholar
Tadmouri, G. O., Nair, P., Obeid, T., Al Ali, M. T., Al Khaja, N. & Hamamy, H. A. (2009) Consanguinity and reproductive health among Arabs. Reproductive Health 6, 17.CrossRefGoogle ScholarPubMed
Tuncbilek, E. & Koc, I. (1994) Consanguineous marriage in Turkey and its impact on fertility and mortality. Annual Human Genetics 58, 321329.CrossRefGoogle ScholarPubMed