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The association of traumatic brain injury with rate of progression of cognitive and functional impairment in a population-based cohort of Alzheimer's disease: the Cache County dementia progression study by Gilbert et al. Late effects of traumatic brain injury on dementia progression

Published online by Cambridge University Press:  03 September 2014

David J. Sharp
David J. Sharp*
Affiliation:
National Institute of Health (NIHR) Research Professor, The Computational, Cognitive and Clinical Neuroimaging Laboratory, 3rd Floor, Burlington Danes Building, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK. Email: david.sharp@imperial.ac.uk
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Extract

There is compelling evidence that traumatic brain injury (TBI) can trigger neurodegeneration, and that this is a major determinant of long-term outcome (Smith et al., 2013). A single significant injury such as a road traffic accident or exposure to a bomb blast can predispose an individual to Alzheimer's disease (AD), and here Gilbert and colleagues show for the first time that a history of TBI also alters the progression the disease.

Type
Commentary paper of the month
Information
International Psychogeriatrics , Volume 26 , Issue 10 , October 2014 , pp. 1591 - 1592
Copyright
Copyright © International Psychogeriatric Association 2014 

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