CJO - Abstract - Small cell neuroendocrine carcinoma in the petrous apex

The Journal of Laryngology & Otology (2006), 120: 74-76 Cambridge University Press

Copyright © 2005 JLO (1984) Limited

doi:10.1017/S0022215105003099

Published online by Cambridge University Press 25 Nov 2005

Clinical Record

Small cell neuroendocrine carcinoma in the petrous apex

Lana Kovac ^a1^c1 , Mislav Gjuric ^a1 , Srecko Branica ^a1 , Krsto Dawidowsky ^a1 and Sven Seiwerth ^a2
^a1 Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center, Zagreb, Croatia
^a2 Department of Pathology, University Hospital Zagreb, Zagreb, Croatia

Article author query

kovaccaron; l [Medline] [Google Scholar]

gjuricacute; m [Medline] [Google Scholar]

branica s [Medline] [Google Scholar]

dawidowsky k [Medline] [Google Scholar]

seiwerth s [Medline] [Google Scholar]

Abstract

With the exception of moderately differentiated neuroendocrine carcinoma of the larynx, neuroendocrine carcinomas are very rare head and neck malignancies. We report a case of a small cell neuroendocrine carcinoma in the petrous apex of the temporal bone. This unusual site for this tumour has not yet been reported in the literature. We confirmed the location and extent of the primary tumour by positron-emission tomography scan. The final histopathological diagnosis was of small cell carcinoma, and this was confirmed by immunohistochemistry. We treated this patient with surgery followed by radiotherapy and chemotherapy. After the treatment was completed there was subtotal remission of the tumour, with no distant metastases.

(Accepted July 14 2005)

Key Words: Carcinoma; Neuroendocrine; Carcinoma; Small Cell; Temporal Bone; Skull Base.

Correspondence:
^c1 Address for correspondence: Lana Kovac, MD, Savska cesta 3, HR-10 000 Zagreb, Croatia. E-mail: dkovac@kbc-zagreb.hr