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Epithelial-myoepithelial carcinoma of the parotid gland. An unusual cause of ear canal stenosis

Published online by Cambridge University Press:  29 June 2007

D. P. C. Lau ,
M. J. Goddard ,
I. D. Bottrill  and
D. A. Moffat
D. P. C. Lau*
Affiliation:
Department of Otolaryngology, Addenbrookes Hospital, Hills Road, Cambridge, UK.
M. J. Goddard
Affiliation:
Department of Histopathology, Addenbrookes Hospital, Hills Road, Cambridge, UK.
I. D. Bottrill
Affiliation:
Department of Otolaryngology, Addenbrookes Hospital, Hills Road, Cambridge, UK.
D. A. Moffat
Affiliation:
Department of Otolaryngology, Addenbrookes Hospital, Hills Road, Cambridge, UK.
*
Address for correspondence: Dr David Lau, Department of Otolaryngology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ. Fax: 01223 217559
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Abstract

Epithelial-myoepithelial carcinoma (EMC) accounts for approximately one per cent of salivary gland tumours. This tumour is gaining wider recognition following inclusion into the WHO histological classification of salivary gland tumours in 1990. Salivary gland tumours characteristically present with an enlarging mass. We describe an unusual presentation of a salivary gland tumour with stenosis of the external ear canal in the absence of a palpable mass. EMC usually arises from the salivary glands but isolated cases have been described arising primarily from the paranasal sinuses, trachea and lacrimal gland. The management of this tumour is still evolving with surgical excision being the main-stay of treatment. The efficacy of radiotherapy has not yet been established but high local recurrence rates despite apparently adequate excision and the possibility of a multicentric origin of the tumour may herald an increasing role for radiotherapy in the future. We stress the importance of awareness of adjacent structures when considering the cause of cartilaginous canal stenosis.

Keywords

Salivary gland neoplasmsEar canalCarcinoma
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 5 , May 1996 , pp. 493 - 495
Copyright
Copyright © JLO (1984) Limited 1996

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References

Batsakis, J. G., El-Naggar, A. K., Luna, M. A. (1992) Epithelial-myoepithelial carcinoma of salivary glands. Annals of Otology, Rhinology and Laryngology 101: 540–542.CrossRefGoogle ScholarPubMed
Collina, G., Gale, N., Visona, A., Betts, C. M., Cenacchi, V., Eusebi, V. (1991) Epithelial-myoepithelial carcinoma of the parotid gland: a clinico-pathologic and immunohistochemical study of seven cases. Tumori 77: 257–263.CrossRefGoogle ScholarPubMed
Corio, R. L., Sciubba, J. J., Brannon, R. B., Batsakis, J. G. (1982) Epithelial-myoepithelial carcinoma of intercalated duct origin: a clinicopathologic and ultrastructural assessment of sixteen cases. Oral Surgery, Oral Medicine, Oral Pathology 53: 280–287.CrossRefGoogle ScholarPubMed
Di Palma, S. (1994) Epithelial-myoepithelial carcinoma with co-existing multifocal intercalated duct hyperplasia of the parotid gland. Histopathology 25: 494–496.CrossRefGoogle ScholarPubMed
Donath, K., Seifert, G., Schmitz, R. (1972) Zur diagnose und ultrastruktur des tubulären speichgangcarcinoms. Epithelial-myoepitheliales schaltstrückcarcinom. Virchows Archiv A Pathological Anatomy and Histopathology 356: 16–31.Google Scholar
Fonseca, I., Soares, J. (1993) Epithelial-myoepithelial carcinoma of the salivary glands. A study of 22 cases. Virchows Archives A. Pathological Anatomy and Histopathology 422: 389–396.CrossRefGoogle ScholarPubMed
Hamper, K., Brugmann, M., Koppermann, R., Caselitz, J., Arps, H., Askensten, U., Auer, G., Seifert, G. (1989) Epithelial-myoepithelial duct carcinoma of salivary glands: a follow-up and cytophotometric study of 21 cases. Journal of Oral Pathology and Medicine 18: 299–304.CrossRefGoogle ScholarPubMed
Horinouchi, H., Ishihara, T., Kawamura, M., Kato, R., Kikuchi, K., Kobayashi, K., Maenaka, Y., Torikata, C. (1993) Epithelial myoepithelial tumour of the tracheal gland. Journal of Clinical Pathology 46: 185–187.CrossRefGoogle ScholarPubMed
Luna, M. A., Ordonez, N. G., Mackay, B., Batsakis, J. G., Guillamondegui, O. (1985) Salivary epithelial-myoepithelial carcinomas of intercalated ducts: a clinical, electron microscopic and immunocytochemical study. Oral Surgery, Oral Medicine, Oral Pathology 59: 482–490.CrossRefGoogle ScholarPubMed
Luna, M. A., Batsakis, J. G., Ordonez, N. G., Mackay, B., Tortoledo, M. E. (1987) Salivary gland adenocarcinomas. A clinicopathologic analysis of three distinct types. Seminars in Diagnostic Pathology 4: 117–135.Google Scholar
Morinaga, S., Hashimoto, S., Tezuka, F. (1992) Epithelialmyoepithelial carcinoma of the parotid gland in a child. Acta Pathologica Japonica 42: 358–363.CrossRefGoogle ScholarPubMed
Noel, S., Brozna, J. P. (1992) Epithelial-myoepithelial carcinoma of salivary gland with metastasis to lung: report of a case and review of the literature. Head and Neck 14: 401–406.CrossRefGoogle ScholarPubMed
Ostrowski, M. L., Font, R. L., Halpern, J., Nicolitz, E., Barnes, R. (1993) Clear cell epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the lacrimal gland. Ophthalmology 101: 925–930.CrossRefGoogle Scholar
Seifert, G., Brocheriou, C.Cardesa, A., Eveson, J. W. (1990) WHO international histological classification of tumours. Tentative histological classification of salivary gland tumours. Pathology, Research and Practice 186: 555–581.CrossRefGoogle ScholarPubMed
Simpson, R. H. W., Clarke, T. J., Sarsfield, P. T. L., Gluckman, P. G. C. (1991) Epithelial-myoepithelial carcinoma of salivary glands. Journal of Clinical Pathology 44: 419–423.CrossRefGoogle ScholarPubMed