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A Web-Based Study of Personality, Psychopathology and Substance Use in Twin, Other Relative and Relationship Pairs

Published online by Cambridge University Press:  21 February 2012

Kenneth S. Kendler*
Affiliation:
Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, United States of America; Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, United States of America; Department of Human and Molecular Genetics, Virginia Commonwealth University School of Medicine, Richmond, United States of America. kendler@vcu.edu
John Myers
Affiliation:
Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, United States of America; Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, United States of America.
Jeff Potter
Affiliation:
Atof Inc, Cambridge, United States of America.
Jill Opalesky
Affiliation:
Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Richmond, United States of America; Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, United States of America.
*
*Address for correspondence: Kenneth Kendler, MD, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University Medical School, Box 980126, 800 E. Leigh Street, Room 1–123, Richmond, VA 23298-012, United States of America.

Abstract

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Web-based studies have become increasingly common in the social sciences, but have been rare in genetic epidemiology in general and twin studies in particular. We here review the methods, validity checks and preliminary correlational data from an on-line questionnaire collected from 2005–2008. During this time period, 44,112 individuals completed the questionnaire. This sample was 65.3% female, 85.4% 18 years or older, 72.0% Caucasian and had a mean educational level of 12.2 years. The sample included 609 twin, 333 sibling and 201 parent-offspring pairs as well as 342 dating partners, 313 ‘significant other’ pairs, 327 spouses and 2,316 friend pairs. A range of checks suggested low levels of invalid data. Correlations for personality, substance use and misuse, lifetime major depression, social attitudes, educational status, and height and weight were broadly similar to those obtained previously using conventional assessment methods. Web-based studies are a relatively easy and inexpensive way to ascertain large numbers of individuals, although obtaining twin pairs is more difficult, and female and monozygotic pairs are overrepresented. The sample is diverse and pair resemblance is generally similar to that obtained using interviews or mailed questionnaires.

Type
Articles
Copyright
Copyright © Cambridge University Press 2009