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Weight management as a cardioprotective intervention raises issues for nutritional scientists regarding clinical ethics

Published online by Cambridge University Press:  28 January 2009

Lucy Aphramor
Affiliation:
Coventry University, Coventry, UK
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Abstract

Type
Abstract
Copyright
Copyright © The Author 2009

Weight management through lifestyle change is an accepted recommendation in the primary prevention and secondary treatment of CHD in UK policy (British Association for Cardiac Rehabilitation (BACR) guidelines(Reference Coats, McGee, Stokes and Thompson1) and underpins European-wide programmes(Reference Graham, Atar and Borch-Johnsen2). However, it is also recognised that weight management remains an elusive goal for most patients(Reference Mann, Tomiyama, Westling, Lew, Samuels and Chatman3) and that lifestyle change can improve metabolic risk independent of weight loss(Reference Bacon, Stern, Van Loan and Keim4). Thus, cardioprotective dietary treatment decisions raise ethical issues for nutritional scientists that have not been widely debated(Reference Aphramor5).

The study relied on two methodologies. First, it used standard techniques from evidence-based medicine(6) to assess the appropriateness of papers cited in support of weight-loss recommendations in UK and European-wide CHD management programmes. Two examples are given here. Second, it interrogated these findings within the parameters of an established bioethical framework(Reference Beauchamp and Childress7) considering fidelity, veracity, justice, a caring response, beneficence and nonmaleficence. It considered claims for the clinical effectiveness of weight management in CHD management with reference to two key systematic reviews(Reference Mann, Tomiyama, Westling, Lew, Samuels and Chatman3, Reference Mead, Atkinson and Albin8). The first systematic review(Reference Mann, Tomiyama, Westling, Lew, Samuels and Chatman3) has evaluated the evidence for the effectiveness of energy restriction in achieving sustained weight loss. The authors conclude that rather than supporting energy restriction for (cardiac) health, evidence to date implicates dieting in adverse health outcomes, including concern about weight cycling on all-cause and cardiac mortality. The second review(Reference Mead, Atkinson and Albin8) is a systematic review of evidence on dietary advice to prevent further events in individuals with existing CVD. No evidence was found to support a recommendation of weight loss.

To support weight-loss advice, a reference(Reference Reddy9) cited in the BACR guidelines(Reference Coats, McGee, Stokes and Thompson1) in turn cites three papers. The first paper(Reference Van Gaal, Wauters and De Leeuw10) reports on a number of studies investigating weight change in relation to cardiovascular risk factors. It is not a systematic review of the evidence nor does it contain any systematic reviews. The parameters of the trials included (e.g. n 9; 10 weeks duration) render it unsuitable to support the claims made for it(6); the original authors qualify their statements throughout: ‘the possible effects of exercise were difficult to determine’; ‘it cannot be proven that weight loss per se is the most important trigger of the reduced mortality’; ‘data on the effects of weight loss on Lp(a) are scarce and contradictory. Further studies are needed.’(Reference Van Gaal, Wauters and De Leeuw10). Claims for benefits of weight loss are inadequately referenced throughout the European guidelines(6). For example, the statement ‘Intentional weight loss in obese patients can improve or prevent many of the obesity-related risk factors for CHD’ is not supported by a citation. Further, it is contradicted by the evidence(Reference Mann, Tomiyama, Westling, Lew, Samuels and Chatman3, Reference Mead, Atkinson and Albin8). Other studies used by European programmes to support weight-loss claims are inappropriate: one even has no methodology(Reference Anderson and Konz11). Hence, references cited in the literature to support weight-loss recommendations in patients with a BMI >25 kg/m2 are not fit for purpose. Clearly, this misrepresentation of data in CHD guidelines is methodologically problematic.

There are also ethical implications related to maleficence and nonmaleficence. This finding has implications for nutritional scientists in terms of professional duty, accountability, informed consent, clinical effectiveness and research directions.

References

1. Coats, A, McGee, H, Stokes, H & Thompson, D (2007) BACR Guidelines for Cardiac Rehabilitation. Oxford: Blackwell Science Ltd.Google Scholar
2. Graham, I, Atar, B, Borch-Johnsen, K et al. (2007) Eur Heart J 14, Suppl. 2, E1E40.Google Scholar
3. Mann, T, Tomiyama, AJ, Westling, E, Lew, AM, Samuels, B & Chatman, J (2007) Am Psychol 62, 220233.CrossRefGoogle Scholar
4. Bacon, L, Stern, JS, Van Loan, MD & Keim, NL (2005) J Am Diet Assoc 105, 929936.CrossRefGoogle Scholar
5. Aphramor, L (2005) Soc Theory Health 3, 315340.CrossRefGoogle Scholar
6. Public Health Resource Unit (2008) Appraisal tools. http://www.phru.nhs.uk/Pages/PHD/resources.htmGoogle Scholar
7. Beauchamp, T & Childress, F (2001) Principles of Biomedical Ethics, 5th ed. Oxford: Oxford University Press.Google Scholar
8. Mead, A, Atkinson, G, Albin, D et al. (2006) J Hum Nutr Diet 19, 401419.CrossRefGoogle Scholar
9. Reddy, S (2006) Care pathway for the management of overweight and obesity. Part of the Your weight, your health series. http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_4134408Google Scholar
10. Van Gaal, LF, Wauters, MA & De Leeuw, IH (1997) Int J Obes Relat Metab Disord 21, Suppl. 1, S5S9.Google Scholar
11. Anderson, W & Konz, E (2001) Obes Res 9, Suppl. 4, 326S334S.Google Scholar