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Initial response to drugs in depressive illness and psychiatric and community adjustment a year later

Published online by Cambridge University Press:  09 July 2009

Allen Raskin*
Affiliation:
Psychopharmacology Research Branch, National Institute of Mental Health, Maryland, USA
Helvi Boothe
Affiliation:
Psychopharmacology Research Branch, National Institute of Mental Health, Maryland, USA
Natalie Reatig
Affiliation:
Psychopharmacology Research Branch, National Institute of Mental Health, Maryland, USA
Joy G. Schulterbrandt
Affiliation:
Psychopharmacology Research Branch, National Institute of Mental Health, Maryland, USA
*
1Address for correspondence: Dr Allen Raskin, Psycho-pharmacology Research Branch, National Institute of Mental Health, 5600 Fishers Lane, Room 9–101, Rockville, Maryland 20857, USA.

Synopsis

Three hundred and sixty depressed in-patients initialy treated with imipramine, chlorpromazine or a placebo were re-evaluated a year later. Patients showing the poorest adjustment at one year were those who failed to show a good initial response to treatment and those who responded positively to a placebo.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1978

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