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Stem cells and their potential relevance to paediatric cardiology

Published online by Cambridge University Press:  22 March 2006

Frank Pillekamp ,
Michael Reppel ,
Konrad Brockmeier  and
Jürgen Hescheler
Frank Pillekamp
Affiliation:
Paediatric Cardiology, University of Cologne, Cologne, Germany Institute of Neurophysiology, University of Cologne, Cologne, Germany
Michael Reppel
Affiliation:
Institute of Neurophysiology, University of Cologne, Cologne, Germany
Konrad Brockmeier
Affiliation:
Paediatric Cardiology, University of Cologne, Cologne, Germany
Jürgen Hescheler
Affiliation:
Institute of Neurophysiology, University of Cologne, Cologne, Germany
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Abstract

Basic scientists, as well as cardiologists, are caught by the idea of curing ischaemic heart disease with cardiac progenitor or stem cells. This short review provides an overview of our current knowledge on the potential use of stem cells for cardiac disease. Since, in infants and children, aetiologies and pathomechanisms of critical cardiac disease are fundamentally different from those in adults, we will also address the question as to whether such young patients could be a therapeutic target at all, and in which respect it may be necessary to view treatment with stem cells from a different stance in the developing organism.

Keywords

Pluripotent stem cellbioprosthesiscardiovascular diseasestherapy
Type
Continuing Medical Education
Information
Cardiology in the Young , Volume 16 , Issue 2 , April 2006 , pp. 117 - 124
Copyright
© 2006 Cambridge University Press

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