Hostname: page-component-8448b6f56d-mp689 Total loading time: 0 Render date: 2024-04-16T10:32:12.174Z Has data issue: false hasContentIssue false
  • English
  • Français

Nanophase Alumina/Poly(L-Lactic Acid) Composite Scaffolds for Biomedical Applications

Published online by Cambridge University Press:  11 February 2011

Aaron J. Dulgar Tulloch ,
Rena Bizios  and
Richard W. Siegel
Aaron J. Dulgar Tulloch
Affiliation:
Department of Materials Science and Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
Rena Bizios
Affiliation:
Department of Biomedical Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
Richard W. Siegel
Affiliation:
Department of Materials Science and Engineering, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA Rensselaer Nanotechnology Center, Rensselaer Poytechnic Institute, Troy, NY 12180–3590, USA
Get access

Abstract

Three-dimensional composites of nanophase alumina and poly(L-lactic acid) with an interconnected porous network and an overall porosity in excess of 90% are cytocompatible. Osteoblast proliferation on the nanophase ceramic/polymer composites is a function of time of cell culture and of nanoceramic loading in the biomaterial substrates.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 740: Symposium I – Nanomaterials for Structural Applications , 2002 , I6.3
Copyright
Copyright © Materials Research Society 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Webster, T.J., Siegel, R.W., Bizios, R., Nanostruct. Mater. 12:983 1999 Google Scholar
2. McManus, A.J., Master's Thesis, Rensselaer Poytechnic Institute, Troy, NY 2001 Google Scholar
3. Webster, T.J., Siegel, R.W., Bizios, R., Biomaterials 20:1222 1999 Google Scholar
4. Webster, T.J., Siegel, R.W., Bizios, R., Biomaterials 21:1803 2000 Google Scholar
5. Webster, T.J., Ergun, C., Doremus, R.H., Siegel, R.W., Bizios, R., Biomed, J.. Mater. Res. 51:475 2000 Google Scholar
6. Webster, T.J., Schadler, L.S., Siegel, R.W., Bizios, R., Tissue Eng. 7:291 2001 Google Scholar
7. Zhang, R., Ma, P.X., Biomed, J.. Mater. Res. 44:446 1999 Google Scholar
8. ASTM D 1621–00Google Scholar
9. Puleo, D.A., Holleran, L.H., Doremus, R.H., Bizios, R., J. Biomed. Mat. Res. 25:711 1991 Google Scholar
10. Lam, K.H., Nieuwenhuis, P., Molenaar, I., Esselbrugge, H., Feijen, J., Dijkstra, P.J., Schakenraad, J.M., J. Mater. Sci.: Matls. in Med. 5:181 1994 Google Scholar
11. Ishaug, S.L., Crane, G.M., Miller, M.J., Yasko, A.W., Yazemski, M.J., Mikos, A.G., J Biomed. Mater. Res. 36:17 1997 Google Scholar
12. Ma, P.X., Zhang, R., Xiao, G., Franceschi, R., J. Biomed. Mater. Res. 54:284 2001 Google Scholar
13. Sikavitsas, V.I., Bancroft, G.N., Mikos, A.G., J. Biomed. Mater. Res. 62:136 2002 Google Scholar