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Embryonic Stem Cell–Derived Gametes and Genetic Parenthood: A Problematic Relationship

Published online by Cambridge University Press:  18 December 2007

HEIDI MERTES
Affiliation:
Bioethics Institute Ghent, Belgium
GUIDO PENNINGS
Affiliation:
Ghent University and Bioethics Institute Ghent (BIG), Belgium

Extract

The recent success in generating live offspring from embryonic stem cell (ESC) –derived gametes in mice sparked visions of growing tailor-made sperm for men faced with infertility. However, although this development will almost certainly lead to new insights into the processes underlying spermatogenesis and thus in the possible causes of male infertility, it is less certain if deriving sperm from ES cells, which are in turn derived from a sterile man, can make someone a genetic parent. As the gap between newly envisioned reproductive technologies and natural reproduction widens, the question thus needs to be asked if these possible therapies still lead to genetic parenthood.

Type
SPECIAL SECTION: OPEN FORUM
Copyright
© 2008 Cambridge University Press

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