Hostname: page-component-76fb5796d-dfsvx Total loading time: 0 Render date: 2024-04-27T00:32:56.855Z Has data issue: false hasContentIssue false

A comparative costs analysis of brachytherapy and Radical Retropubic Prostatectomy therapies for clinically localized prostate cancer

Published online by Cambridge University Press:  21 July 2009

Maria Michela Gianino
Affiliation:
University of Turin
Mario Galzerano
Affiliation:
University of Turin
Davide Minniti
Affiliation:
San Giovanni Battista University Hospital
Cinzia Di Novi
Affiliation:
University of Eastern Piedmont
Barbara Martin
Affiliation:
University of Turin
Ottavio Davini
Affiliation:
San Giovanni Battista University Hospital
Silvana Barbaro
Affiliation:
San Giovanni Battista University Hospital

Abstract

Objectives: The aim of this study is to perform a comparative costs analysis of brachytherapy (BT) and radical retropubic prostatectomy (RRP) for clinically localized prostate cancer and to shed light on the difficulties of comparing their relative economic effectiveness.

Methods: A systematic literature review of costing studies available in the Medline, Embase, DARE, and INAHTA databases.

Results: There is a lack of homogeneity among published studies in this field. Differences in the reported costs are related to different environments in which the two techniques (BT and RRP) are applied, and in particular due to the use of different methodology, cost items included, time frames, and different price levels in different settings.

Conclusion: Published studies of costing data of BT and RRP do not provide clear-cut evidence for a conclusion about which treatment may be more effective from an economic point of view.

Type
Research Reports
Copyright
Copyright © Cambridge University Press 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

1. Alexianu, M, Weiss, GH. Radical prostatectomy versus brachytherapy for early-stage prostate cancer. J Endourol. 2000;14:325328.CrossRefGoogle ScholarPubMed
2. Alton, V, Eckerlund, I, Norlund, A. Health economic evaluations: How to find them. Int J Technol Assess Health Care. 2006;22:512517.CrossRefGoogle Scholar
3. Barry, MJ. Clinical practice. Prostate-specific-antigen testing for early diagnosis of prostate cancer. N Engl J Med. 2001;344:13731377.CrossRefGoogle ScholarPubMed
4. Bill-Axelson, A, Holmberg, L, Ruutu, M, et al. Scandinavian Prostate Cancer Group Study No. 4: Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med. 2005;352:19771984.CrossRefGoogle Scholar
5. Brandeis, J, Pashos, CL, Henning, JM, Litwin, MS. A nationwide charge comparison of the principal treatments for early stage prostate carcinoma. Cancer. 2000;89:17921799.3.0.CO;2-4>CrossRefGoogle ScholarPubMed
6. Burkhardt, JH, Litwin, MS, Rose, CM, et al. Comparing the costs of radiation therapy and radical prostatectomy for the initial treatment of early-stage prostate cancer. J Clin Oncol. 2002;20:28692875.CrossRefGoogle ScholarPubMed
7. Buron, C, Le Vu, B, Cosset, JM, et al. Brachytherapy versus prostatectomy in localized prostate cancer: Results of a French multicenter prospective medico-economic study. Int J Radiat Oncol Biol Phys. 2007;67:812822.CrossRefGoogle ScholarPubMed
8. Canadian Task Force on Preventive Health Care. 1997. Canadian Task Force methodology. http://www.ctfphc.org/methods.htm.Google Scholar
9. Ciezki, JP, Klein, EA, Angermeier, KW, et al. Cost comparison of radical prostatectomy and transperineal brachytherapy for localized prostate cancer. Urology. 2000;55:6872.CrossRefGoogle ScholarPubMed
11. Drummond, MF, Stoddart, GL, Torrance, GW. Methods for the economic evaluation of health care programmes. Oxford: Oxford University Press; 1987.Google Scholar
12. European Commission. 2009. http://ec.europa.eu/index_en.htm.Google Scholar
13. Gianino, MM, Galzerano, M, Tizzani, A, Gontero, P. Critical issues in current comparative and cost analyses between retropubic and robotic radical prostatectomy. BJU Int. 2008;101:23.CrossRefGoogle ScholarPubMed
14. Heidenreich, A, Aus, G, Bolla, M, et al. EAU guidelines on prostate cancer. Eur Urol. 2008;53:6880.CrossRefGoogle ScholarPubMed
16. Hummel, S, Paisley, S, Morgan, A, Currie, E, Brewer, N. Clinical and cost-effectiveness of new and emerging technologies for early localised prostate cancer: A systematic review. Health Technol Assess. 2003;7:1157.CrossRefGoogle ScholarPubMed
17. Kohan, AD, Armenakas, NA, Fracchia, JA. The perioperative charge equivalence of interstitial brachytherapy and radical prostatectomy with 1-year followup. J Urol. 2000;163:511514.CrossRefGoogle ScholarPubMed
18. Makhlouf, AA, Boyd, JC, Chapman, TN, Theodorescu, D. Perioperative costs and charges of prostate brachytherapy and prostatectomy. Urology. 2002;60:656660.CrossRefGoogle ScholarPubMed
19. Norderhaug, I, Dahl, O, Høisaeter, PA, et al. Brachytherapy for prostate cancer: A systematic review of clinical and cost effectiveness. Eur Urol. 2003;44:4046.CrossRefGoogle ScholarPubMed
20. Penson, DF, Schonfeld, WH, Flanders, SC, et al. Relationship of first-year costs of treating localized prostate cancer to initial choice of therapy and stage at diagnosis: Results from the CAPSURE database. Urology. 2001;57:499503.CrossRefGoogle ScholarPubMed
21. U.S. Bureau of Labor Statistics—Agency for the Federal Government. 2009. http://www.bls.gov/.Google Scholar
22. Wagner, TT III, Young, D, Bahnson, RR. Charge and length of hospital stay analysis of radical retropubic prostatectomy and transperineal prostate brachytherapy. J Urol. 1999;161:12161221.CrossRefGoogle ScholarPubMed