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Consciousness, cortical function, and pain perception in nonverbal humans

Published online by Cambridge University Press:  01 May 2007

K. J. S. Anand
Affiliation:
Department of Pediatrics, Anesthesiology, Neurobiology & Developmental Sciences, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, AR 72202 Pain Neurobiology Laboratory, Arkansas Children's Hospital Research Institute, Little Rock, AR 72202. anandsunny@uams.edu

Abstract

Postulating the subcortical organization of human consciousness provides a critical link for the construal of pain in patients with impaired cortical function or cortical immaturity during early development. Practical implications of the centrencephalic proposal include the redefinition of pain, improved pain assessment in nonverbal humans, and benefits of adequate analgesia/anesthesia for these patients, which certainly justify the rigorous scientific efforts required.

Type
Open Peer Commentary
Copyright
2007 Cambridge University Press

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