British Journal of Nutrition

Systematic Reviews

Tea consumption and mortality of all cancers, CVD and all causes: a meta-analysis of eighteen prospective cohort studies

Jun Tanga1 , Ju-Sheng Zhenga1 , Ling Fanga2, Yongxin Jina2, Wenwen Caia1 and Duo Lia1 c1

a1 Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, People’s Republic of China

a2 Second Provincial People’s Hospital of Gansu, Lanzhou 730000, People’s Republic of China

Abstract

Epidemiological studies have demonstrated inconsistent associations between tea consumption and mortality of all cancers, CVD and all causes. To obtain quantitative overall estimates, we conducted a dose–response meta-analysis of prospective cohort studies. A literature search in PubMed and Embase up to April 2015 was conducted for all relevant papers published. Random-effects models were used to calculate pooled relative risks (RR) with 95 % CI. In eighteen prospective studies, there were 12 221, 11 306 and 55 528 deaths from all cancers, CVD and all causes, respectively. For all cancer mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 1·06 (95 % CI 0·98, 1·15) and 0·79 (95 % CI 0·65, 0·97), respectively. For CVD mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 0·67 (95 % CI 0·46, 0·96) and 0·88 (95 % CI 0·77, 1·01), respectively. For all-cause mortality, the summary RR for the highest v. lowest category of green tea and black tea consumption were 0·80 (95 % CI 0·68, 0·93) and 0·90 (95 % CI 0·83, 0·98), respectively. The dose–response analysis indicated that one cup per d increment of green tea consumption was associated with 5 % lower risk of CVD mortality and with 4 % lower risk of all-cause mortality. Green tea consumption was significantly inversely associated with CVD and all-cause mortality, whereas black tea consumption was significantly inversely associated with all cancer and all-cause mortality.

(Received December 17 2014)

(Revised May 07 2015)

(Accepted June 01 2015)

(Online publication July 23 2015)

Key words

  • Tea;
  • Mortality;
  • Cancers;
  • CVD;
  • All-cause mortality;
  • Meta-analyses

Correspondence

c1 Corresponding author: Professor D. Li, fax +86 571 8898 2024, email duoli@zju.edu.cn

Footnotes

  These authors contributed equally to the present work.

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