Hostname: page-component-8448b6f56d-cfpbc Total loading time: 0 Render date: 2024-04-16T00:36:32.871Z Has data issue: false hasContentIssue false

Shaping Vulnerable Bodies at the Thin Boundary between Environment and Organism: Skin, DNA Repair, and a Genealogy of DNA Care Strategies

Published online by Cambridge University Press:  10 August 2015

Alexander von Schwerin*
Affiliation:
Max Planck Institute for the History of Science E-mail: schwerin@mpiwg-berlin.mpg.de

Argument

This paper brings together the history of risk and the history of DNA repair, a biological phenomenon that emerged as a research field in between molecular biology, genetics, and radiation research in the 1960s. The case of xeroderma pigmentosum (XP), an inherited hypersensitivity to UV light and, hence, a disposition to skin cancer will be the starting point to argue that, in the 1970s and 1980s, DNA repair became entangled in the creation of new models of the human body at risk – what is here conceptually referred to as the vulnerability aspect of body history – and new attempts at cancer prevention and enhancement of the body associated with the new flourishing research areas of antimutagenesis and anticarcinogenesis. The aim will be to demonstrate that DNA repair created special attempts at disease prevention: molecular enhancement, seeking to identify means to increase the self-repair abilities of the body at the molecular level. Prevention in this sense meant enhancing the body's ability to cope with the environmental hazards of an already toxic world. This strategy has recently been adopted by the beauty industry, which introduced DNA care as a new target for skin care research and anti-aging formulas.

Type
Topical Section: Surfaces in the History of Modern Science: Inscribing, Separating, Enclosing
Copyright
Copyright © Cambridge University Press 2015 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmend, Sara, and Stacey, Jackie, eds. 2001. Thinking Through the Skin. London: Routledge.Google Scholar
Anon. 2015. “Can This New Miracle Product Reverse the Effects of Sun Damage?” 22 January 2015, www.elle.com/beauty/makeup-skin-care/a26140/anti-aging-skin-cancer/ (last accessed on March 29, 2015).Google Scholar
Anziou, Didier. 1989. The Skin Ego. New Haven CT: Yale University Press.Google Scholar
Aronowitz, Robert A. 1998. Making Sense of Illness: Science, Society, and Disease. New York: Cambridge University Press.Google Scholar
Auerbach, Charlotte. 1976. Mutation Research: Problems, Results and Perspectives. London: Chapman and Hall.CrossRefGoogle Scholar
Bächi, Beat. 2009. Vitamin C für alle! Pharmazeutische Produktion, Vermarktung und Gesundheitspolitik (1933–1953). Zürich: Chronos.Google Scholar
Bächi, Beat. 2010. “Zur Krise der westdeutschen Grenzwertpolitik in den 1970er Jahren: Die Verwandlung des Berufskrebses von einem toxikologischen in ein sozioökonomisches Problem.” Berichte zur Wissenschaftsgeschichte 33:419435CrossRefGoogle Scholar
Bächi, Beat, and Reinhardt, Carsten. 2010. “Einleitung: Zur Geschichte des Regulierungswissens. Grenzen der Erkenntnis und Möglichkeiten des Handelns.” Berichte zur Wissenschaftsgeschichte 33:347350.CrossRefGoogle Scholar
Bauer, Susanne. 2003. “Krankheit im Raster des Umweltgenomprojektes: Koordination, Lokalisation und Fakten auf der Flucht.” In Rasterfahndungen: Darstellungstechniken, Normierungsverfahren, Wahrnehmungskonstitution, edited by Nusser, Tania and Strowick, Elisabeth, 199218. Bielefeld: transcript.CrossRefGoogle Scholar
Beatty, John. 1991. “Genetics in the Atomic Age: The Atomic Bomb Casualty Commission, 1947–1956.” In The Expansion of American Biology, edited by Benson, Keith R., Maienschein, Jane, and Rainger, Ronald, 284324. New Brunswick NJ: Rutgers University Press.Google Scholar
Beers, Roland F. 1972. “Introductory Remarks.” In Molecular and Cellular Repair Processes. Fifth International Symposium on Molecular Biology, Baltimore, Maryland, June 3–4, 1971, edited by Beers, Roland F., Herriott, Roger M., and Tilghman, R. Carmichael, xv-xviii. Baltimore: Johns Hopkins University Press.Google Scholar
Beiersdorf Inc. 2006. Fitmacher für die gestresste Haut. Press release from 11 September 2006, www.beiersdorf.de/Press_Media_Relations/Pressemitteilungen (last accessed November 26, 2010).Google Scholar
Beiersdorf Inc., Corporate Identity & Information, ed. 2007. Annual Report 2006. Hamburg.Google Scholar
Benthien, Claudia. 2002. Skin: On the Cultural Border between Self and the World. New York: Columbia University Press.Google Scholar
Bonah, Christian, Cantor, David, and Doerries, Matthias, eds. 2010. Meat, Medicine, and Human Health in the Twentieth Century. London: Pickering & Chatto.Google Scholar
Boudia, Soraya. 2013. “From Threshold to Risk: Exposure to Low Doses of Radiation and Its Effects on Toxicants Regulation.” In Toxicants, Health and Regulation since 1945, edited by Boudia, Soraya and Jas, Nathalie, 7187. London: Pickering & Chatto.Google Scholar
Boudia, Soraya. 2014. “Gouverner par les instruments économiques: La trajectoire de l’analyse coût-bénéfice dans l’action publique.” In Le gouvernement de technoscience. Gouverner le progrès et ses dégâts depuis 1945, edited by Pestre, Dominique, 231259. Paris: Éditions La Découverte.CrossRefGoogle Scholar
Boudia, Soraya, and Jas, Nathalie. 2007. “Risk and ‘Risk Society’ in Historical Perspective.” History and Technology 23:317331.CrossRefGoogle Scholar
Boudia, Soraya, and Jas, Nathalie, eds. 2014. Powerless Science? Science and Politics in a Toxic World. New York, Oxford: Berghan Books.Google Scholar
Briesen, Detlef. 2010. Das gesunde Leben: Ernährung und Gesundheit seit dem 18. Jahrhundert. Frankfurt: Campus.Google Scholar
Bröckling, Ulrich. 2007. Das unternehmerische Selbst: Soziologie einer Subjektivierungsform. Frankfurt: Suhrkamp.Google Scholar
Bröckling, Ulrich, Krasmann, Susanne, and Lemke, Thomas, eds. 2011. Governmentality: Current Issues and Future Challenges. London, New York: Routledge.Google Scholar
Cairns, John. 1975. “The Cancer Problem.” Scientific American 233:6478.CrossRefGoogle ScholarPubMed
Cantor, David. 2012a. “Between Prevention and Therapy: Gio Batta Gori and the National Cancer Institute's Diet, Nutrition and Cancer Programme, 1974–1978.” Medical History 56:531561.CrossRefGoogle Scholar
Cantor, David. 2012b. “Introduction: Cancer Control and Prevention in the Twentieth Century.” Bulletin of the History of Medicine 81:138.CrossRefGoogle Scholar
Caplan, Jane. 2000. Written on the Body: The Tattoo in European and American History. Princeton: Princeton University Press.CrossRefGoogle Scholar
Carpenter, Kenneth J. 1988. The History of Scurvy and Vitamin C. Cambridge: Cambridge University Press.Google Scholar
Carter, Simon. 2007. Rise and Shine: Sunlight, Technology and Health. Oxford: Berg.Google Scholar
Castel, Robert. 1981. La gestion des risques: De l’anti-psychiatrie à l’après-psychanalyse. Paris: Les Éditions de Minuit.Google Scholar
Caufield, Catherine. 1989. Multiple Exposures: Chronicles of the Radiation Age. London: Secker & Warburg.Google Scholar
Chen, Nancy N. 2009. Food, Medicine, and the Quest for Good Health: Nutrition, Medicine, and Culture. New York: Columbia University Press.Google Scholar
Choi, S. W., Kim, Y. I., Weitzel, J. N., and Mason, J. B.. 1998. “Folate Depletion Impairs DNA Excision Repair in the Colon of the Rat.” Gut 43:9399.CrossRefGoogle ScholarPubMed
Cleaver, James E. 2001. “Richard B. Setlow: A Commentary on Seminal Contributions and Scientific Controversies.” Environmental and Molecular Mutagenesis 38:122131.CrossRefGoogle Scholar
Cleaver, James E. 2005. “Mending Human Genes: A Job for a Lifetime.” DNA Repair 4:635638.CrossRefGoogle Scholar
Cohen, Leonhard A. 1987. “Diet and Cancer.” Scientific American 257:4248.CrossRefGoogle ScholarPubMed
Connor, Steven. 2004. The Book of Skin. London: Reaktion Books.Google Scholar
Council on Scientific Affairs, American Medical Association. 1993. “Report of the Council on Scientific Affairs. Diet and Cancer: Where Do Matters Stand?Archives of Internal Medicine 153:5056.CrossRefGoogle Scholar
Creager, Angela. 2014. “The Political Life of Mutagens: A History of the Ames Test.” In Powerless Science? Science and Politics in a Toxic World, edited by Boudia, Soraya and Jas, Nathalie, 4664. New York, Oxford: Berghan Books.CrossRefGoogle Scholar
Creager, Angela N. H. 2015. “Radiation, Cancer, and Mutation in the Atomic Age.” Historical Studies in the Natural Sciences 45:1448.CrossRefGoogle Scholar
Creager, Angela N. H., and Santesmases, Maria Jesus. 2006. “Radiobiology in the Atomic Age: Changing Research Practices and Policies in Comparative Perspective.” Journal of the History of Biology 39:637647.CrossRefGoogle Scholar
Davis, Devra. 2007. The Secret History of the War on Cancer. New York: Basic Books.Google Scholar
De Flora, Silvio. 1988. “Problems and Prospects in Antimutagenesis and Anticarcinogenesis.” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:279283.CrossRefGoogle ScholarPubMed
De Flora, Silvio, and Ramel, Claes. 1988. “Mechanisms of Inhibitors of Mutagenesis and Carcinogenesis: Classification and Overview.” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:285306.CrossRefGoogle ScholarPubMed
De Flora, Silvio, Izzotti, Alberto, and Bennicelli, Carlo. 1993. “Mechanisms of Antimutagenesis and Anticarcinogenesis: Role in Primary Prevention.” Basic Life Sciences 61:116.Google ScholarPubMed
Devoret, Raymond. 1979. “Bacterial Tests for Potential Carcinogens.” Scientific American 241:2837.CrossRefGoogle ScholarPubMed
Duden, Barbara. 1991. The Woman beneath the Skin: A Doctor's Patients in Eighteenth-Century Germany. Cambridge MA: Harvard University Press.Google Scholar
Duthie, Susan J. 1999. “Folic Acid Deficiency and Cancer: Mechanisms of DNA Instability.” British Medical Bulletin 55:578592.CrossRefGoogle ScholarPubMed
Fanon, Frantz. 1952. Peau noire, masques blancs. Paris: Éditions du Seuil.Google Scholar
Federal Civil Defense Administration [1951] 2005. “Duck and Cover.” In Atomic Platters: Cold War Music from the Golden Age of Homeland Security, edited by Geerhart, Bill and Sitz, Ken, vol. 6. Translated by Gülden, Jörg. Holste. Bear-Family-Records.Google Scholar
Feldman, Elaine B. 1993. “Dietary Intervention and Chemoprevention—1992 Perspective.” Preventive Medicine 22:661666.CrossRefGoogle ScholarPubMed
Fenton, Alexander, ed. 2000. Order and Disorder: The Health Implications of Eating and Drinking in the Nineteenth and Twentieth Centuries. East Linton: Tuckwell Press.Google Scholar
Flanagan, Mary, and Booth, Austin, eds. 2009. Re:Skin. Cambridge MA: MIT Press.Google Scholar
Fosket, Jennifer. 2002. “Breast Cancer Risk and the Politics of Prevention: Analysis of a Clinical Trial.” Ph.D. diss., University of California, San Francisco.Google Scholar
Fosket, Jennifer. 2004. “Constructing ‘High-Risk Women’: The Development and Standardization of a Breast Cancer Risk Assessment Tool.” Science, Technology & Human Values 29:291313.CrossRefGoogle Scholar
Fox Keller, Evelyn. 2000. The Century of the Gene. Cambridge MA: Harvard University Press.CrossRefGoogle Scholar
Frickel, Scott. 2004. Chemical Consequences: Environmental Mutagens, Scientist Activism, and the Rise of Genetic Toxicology. New Brunswick NJ: Rutgers University Press.Google Scholar
Friedberg, Errol C. 1997. Correcting the Blueprint of Life: An Historical Account of the Discovery of DNA Repair Mechanisms. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.Google Scholar
Friedberg, Errol C. 2004. “The Discovery That Xeroderma Pigmentosum (Xp) Results From Defective Nucleotide Excision Repair.” DNA Repair 3:183195.CrossRefGoogle ScholarPubMed
FTC. 2014. “L’Oréal Settles FTC Charges Alleging Deceptive Advertising for Anti-Aging Cosmetics.” 30 June 2014, www.ftc.gov/news-events/press-releases/2014/06/loreal-settles-ftc-charges-alleging-deceptive-advertising-anti (last accessed on August 14, 2014).Google Scholar
Gaudillière, Jean-Paul. 2010. “Food, Drug and Consumer Regulation: The ‘Meat, DES, and Cancer’ Debates in the United States.” In Meat, Medicine, and Human Health in the Twentieth Century, edited by Cantor, David, Bonah, Christian, and Doerries, Matthias, 179202. London: Pickering & Chatto.Google Scholar
Gilman, Sander L. 2000. Making the Body Beautiful: A Cultural History of Aesthetic Surgery. Princeton: Princeton University Press.Google Scholar
Gormley, T. Ronan, Downey, G., and O’Beirne, D.. 1987. Food, Health and the Consumer: A Report from the FAST Programme of the Commission of the European Communities. London, New York: Elsevier Applied Science.Google Scholar
Greenwald, Peter. 1993. “NCI Cancer Prevention and Control Research.” Preventive Medicine 22:642660.CrossRefGoogle ScholarPubMed
Hacker, Barton C. 1992. “Radiation Safety, the AEC, and Nuclear Weapons Testing.” Public Historian 14:3153.CrossRefGoogle Scholar
Haiken, Elisabeth. 1997. Venus Envy: A History of Cosmetic Surgery. Baltimore: Johns Hopkins University Press.Google Scholar
Haraway, Donna J. 1991. Simians, Cyborgs, and Women: The Reinvention of Nature. New York: Routledge.Google Scholar
Hau, Michael. 2003. The Cult of Health and Beauty in Germany: A Social History, 1890–1930. Chicago: University of Chicago Press.Google Scholar
Hilgartner, Stephen. 2000. Science on Stage: Expert Advice as Public Drama. Stanford: Stanford University Press.CrossRefGoogle Scholar
Horn, David G. 2003. The Criminal Body: Lombroso and the Anatomy of Deviance. New York: Routledge.Google Scholar
Howard-Flanders, Paul. 1981. “Inducible Repair of DNA.” Scientific American 245:5664.CrossRefGoogle ScholarPubMed
Huber, Daniel. 2014. “Die EU-Kosmetikverordnung kommt.” 21 March 2014, www.it-recht-kanzlei.de/eu-kosmetikverordnung.html (last accessed August 14, 2014).Google Scholar
Jas, Nathalie. 2013. “Adapting to ‘Reality’: The Emergence of an International Expertise on Food Additives and Contaminants in the 1950s and the Early 1960s.” In Toxicants, Health and Regulation since 1945, edited by Boudia, Soraya and Jas, Nathalie, 4769. London: Pickering & Chatto.Google Scholar
Kamminga, Harmke, and Cunningham, Andrew, eds. 1995. The Science and Culture of Nutrition, 1840–1940. Amsterdam: Editions Rodopi.CrossRefGoogle ScholarPubMed
Kimball, Richard F. 1969. “Chairman's Opening Remarks.” In Mutation as Cellular Process: A Ciba Foundation Symposium, edited by Wolstenholme, Gordon and O’Connor, Maeve, 12. London: Churchill Ltd.Google Scholar
Kimball, Richard F. 1987. “The Development of Ideas about the Effect of DNA Repair on the Induction of Gene Mutations and Chromosomal Aberrations by Radiation and by Chemicals.” Mutation Research 186:134.CrossRefGoogle ScholarPubMed
Knott, Anja, Mielke, Heiko, Koop, Urte, et al. 2007. “Folic Acid: Cellular Uptake and Penetration into Human Skin.” Journal of Investigative Dermatology 127:24632466.CrossRefGoogle ScholarPubMed
Knott, Anja, Koop, Urte, Mielke, Heiko, et al. 2008. “A Novel Treatment Option for Photoaged Skin.” Journal of Cosmetic Dermatology 7:1522.CrossRefGoogle ScholarPubMed
Körber, Stefan. 1998. Staatliche Steuerung und gesellschaftliche Selbstregulierung in der Chemikalienkontrolle: Eine sozialwissenschaftliche Untersuchung halbstaatlicher Normierung durch den Ausschuß für Gefahrstoffe (Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin. Forschungsbericht 810). Bremerhaven: Wirtschafsverlag NW.Google Scholar
Kraemer, Kenneth H., DiGiovanna, John J., Moshell, Alan N., Tarone, Robert E., and Peck, Gary L.. 1988. “Prevention of Skin Cancer in Xeroderma Pigmentosum with the Use of Oral Isotretinoin.” New England Journal of Medicine 318:16331637.CrossRefGoogle ScholarPubMed
Kuroda, Yukaiki, and Inoue, Tadashi. 1988. “Antimutagenesis by Factors Affecting DNA Repair in Bacteria.” Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 202:387391.CrossRefGoogle ScholarPubMed
Landecker, Hannah. 2011. “Food as Exposure: Nutritional Epigenetics and the New Metabolism.” BioSocieties 6:167194.CrossRefGoogle ScholarPubMed
Langston, Nancy. 2010. Toxic Bodies: Hormone Disruptors and the Legacy of DES. New Haven, London: Yale University Press.Google Scholar
Lengwiler, Martin, and Madarász, Jeannette. 2010. “Präventionsgeschichte als Kulturgeschichte der Gesundheitspolitik.” In Das präventive Selbst: Eine Kulturgeschichte moderner Gesundheitspolitik, edited by Lengwiler, Martin and Madarász, Jeannette, 1128. Bielefeld: transcript.CrossRefGoogle Scholar
Liu, Zen. 2014. “Away with Pseudoscience.” Pacific Standard, 15 October 2014, www.psmag.com/nature-and-technology/cosmetic-companies-get-away-pseudoscience-placebo-week-92455 (last accessed March 29, 2015).Google Scholar
Löwy, Ilana. 1993. “Unscharfe Begriffe und föderative Experimentalstrategien: Die immunologische Konstruktion des Selbst.” In Die Experimentalisierung des Lebens: Experimentalsysteme in den biologischen Wissenschaften 1850/1950, edited by Rheinberger, Hans-Jörg and Hagner, Michael, 188205. Berlin: Wiley-VCH.Google Scholar
Löwy, Ilana. 2012. “Treating Health Risks or Putting Healthy Women at Risk: Controversies around Chemoprevention of Breast Cancer.” In Ways of Regulating Drugs in the 19th and 20th Centuries, edited by Gaudillière, Jean-Paul and Hess, Volker, 206227. Basingstoke: Palgrave.Google Scholar
Lutts, Ralph H. 1985. “Chemical Fallout: Rachel Carson's Silent Spring, Radioactive Fallout, and the Environmental Movement.” Environmental Review 9:210225.CrossRefGoogle ScholarPubMed
Marcus, Alan I. 1994. Cancer from Beef: DES, Federal Food Regulation, and Consumer Confidence. Baltimore: Johns Hopkins University Press.Google Scholar
Martin, Emily. 1994. Flexible Bodies: Tracking Immunity in American Culture – from the Days of Polio to the Age of Aids. Boston: Beacon Press Books.Google Scholar
McGrath, Maria. 2006. “Food for Dissent: A History of Natural Foods and Dietary Health Politics and Culture since the 1960s.” Ph.D. diss., Lehigh University.Google Scholar
Möhring, Maren. 2005. “Working Out the Body's Boundaries: Physiological, Aesthetic, and Psychic Dimensions of the Skin in German Nudism, 1890–1930.” In Body Parts: Critical Explorations in Corporeality, edited by Forth, Christopher and Crozier, Ivan, 229246. Langham MD: Lexington Books.Google Scholar
Mollet, Peter. 1977. “Reparatur in lebenden Zellen.” Bild der Wissenschaft 14:6978.Google Scholar
National Cancer Institute – Division of Cancer and Prevention, ed. 1975. The Carcinogenesis Program. Fiscal Year 1975. Bethesda MD: National Cancer Institute.Google Scholar
National Cancer Institute – Division of Cancer Cause and Prevention, ed. 1983. Annual Report, vol. II, October 1, 1982-September 30, 1983. Bethesda MD: U.S. Government Printing Office.Google Scholar
National Institutes of Health, ed. 1980. Annual Report of Program Activities, National Cancer Institute, Fiscal Year 1980, Part III-B: Division of Cancer Cause and Prevention. Bethesda MD: National Institutes of Health.Google Scholar
National Research Council. 1982. Diet, Nutrition, and Cancer. Washington DC: National Academy Press.Google Scholar
Orland, Barbara, and Spary, Emma C.. 2012. “Introduction to Special Section: Assimilating Knowledge – Food and Nutrition in Early Modern Physiologies.” Studies in History and Philosophy of Biological and Biomedical Sciences 43:317322.CrossRefGoogle Scholar
Petersen, Alan, and Bunton, Robin, eds. 1997. Foucault, Health and Medicine. London, New York: Routledge.Google Scholar
Petersen, Alan R., and Wilkinson, Iain, eds. 2008. Health, Risk, and Vulnerability. London, New York: Routledge.Google Scholar
Porter, Dorothy. 1999. Health, Civilization and the State: A History of Public Health from Ancient to Modern Times. London, New York: Routledge.Google Scholar
Poulter, Sean. 2013. “Banned, Nivea Ad That Made Model of 62 Look Younger.” 27 August 2013, www.dailymail.co.uk/femail/article-2403530/Banned-Nivea-anti-ageing-cream-advert-model-look-younger-digital-airbrushing.html (last accessed on August 10, 2014).Google Scholar
Proctor, Robert N. 1995. Cancer Wars: How Politics Shapes What We Know and Don't Know About Cancer. New York: Basic Books.Google Scholar
Rabinow, Paul. 1996. Essays on the Anthropology of Reason. Princeton: Princeton University Press.Google Scholar
Rader, Karen A. 2004. Making Mice: Standardizing Animals for American Biomedical Research, 1900–1955. Princeton: Princeton University Press.CrossRefGoogle Scholar
Rand, Hannah. 2011. “Bored with Bubble Bath and Perfume Sprays? Latest Trend in Cosmetics Is to EAT Yourself Beautiful.” 15 December 2011, www.dailymail.co.uk (last accessed on March 29, 2015).Google Scholar
Reinarz, Jonathan, and Siena, Kevin, eds. 2013. A Medical History of Skin: Scratching the Surface. London: Pickering & Chatto.Google Scholar
Rheinberger, Hans-Jörg. 1997. Toward a History of Epistemic Things: Synthesizing Proteins in the Test Tube. Stanford: Stanford University Press.Google Scholar
Richards, Evelleen. 1988. “The Politics of Therapeutic Evaluation: The Vitamin C and Cancer Controversy.” In Social Studies of Science 18:653701.CrossRefGoogle Scholar
Rose, Nikolas. 2007. The Politics of Life Itself: Biomedicine, Power, and Subjectivity in the Twenty-First Century. Princeton: Princeton University Press.CrossRefGoogle Scholar
Rudolph, Martin. 2007. “We worked to achieve a milestone right from the start.” In Annual Report 2006, edited by Aktiengesellschaft, Beiersdorf, Corporate Identity & Information, 34. Hamburg 2007.Google Scholar
Rushefsky, Mark E. 1986. Making Cancer Policy. Albany: State University of New York Press.Google Scholar
Sarasin, Philipp. 2001. Reizbare Maschinen: Eine Geschichte des Körpers 1765–1914. Frankfurt: Suhrkamp.Google Scholar
Schnalke, Thomas. 2004. “Casting Skin: Meanings for Doctors, Artists, and Patients.” In Models: The Third Dimension of Science, edited by de Chadarevian, Soraya and Hopwood, Nick, 207241. Stanford: Stanford University Press.CrossRefGoogle Scholar
Schwerin, Alexander. 2009. “Der gefährdete Organismus: Biologie und Regierung der Gefahren am Übergang vom ‘Atomzeitalter’ zur Umweltpolitik (1950–1970).” In Wissensobjekt Mensch: Humanwissenschaftliche Praktiken im 20. Jahrhundert, edited by Vienne, Florence and Brandt, Christina, 187214. Berlin: Kadmos.Google Scholar
Schwerin, Alexander. 2010. “Low Dose Intoxication and a Crisis of Regulatory Models: Chemical Mutagens in the German Research Foundation (DFG), 1963–1973.” Berichte zur Wissenschaftsgeschichte 33:401418.CrossRefGoogle Scholar
Schwerin, Alexander. 2012. “Mutagene Umweltstoffe: Gunter Röhrborn und eine vermeintlich neue eugenische Bedrohung.” In Das Heidelberger Institut für Humangenetik: Vorgeschichte und Ausbau (1962–2012), edited by Cottebrune, Anne and Eckart, Wolfgang U., 106129. Heidelberg: C. R. Bartram.Google Scholar
Schwerin, Alexander. 2013. “From Agriculture to Genomics: The Animal Side of Human Genetics and the Organization of Model Organisms in the Longue Durée.” In Human Heredity in the Twentieth Century, edited by Gausemeier, Bernd, Müller-Wille, Staffan, and Ramsden, Edmund, 113125. London: Pickering & Chatto.Google Scholar
Schwerin, Alexander. 2014. “Vom Gift im Essen zu chronischen Umweltgefahren: Lebensmittelzusatzstoffe und die risikopolitische Institutionalisierung der Toxikogenetik in der Bundesrepublik, 1955–1964.” Technikgeschichte 81:251274.CrossRefGoogle Scholar
Schwerin, Alexander. 2015 (Forthcoming). “Cyclamates: A Tale of Uncertain Knowledge (1930s–1980s).” In Hazardous Substances: Agents of Risk and Change (1800–2000), edited by Erker, Paul, Homburg, Ernst, and Vaupel, Elisabeth. New York: Berghahn Books.Google Scholar
Seidel, Robert W. 1986. “A Home for Big Science: The Atomic Energy Commission's Laboratory System.” Historical Studies in the Physical and Biological Sciences 16:135175.CrossRefGoogle Scholar
Sellers, Christopher C. 1997a. Hazards of the Job: From Industrial Disease to Environmental Health Science. Chapel Hill: University of North Carolina Press.Google Scholar
Sellers, Christopher C. 1997b. “Discovering Environmental Cancer: Wilhelm Hueper, Post-World War II Epidemiology, and the Vanishing Clinician's Eye.” American Journal of Public Health 87:18241835.CrossRefGoogle ScholarPubMed
Sestili, Mary Ann, ed. 1984. Chemoprevention Clinical Trials: Problems and Solutions (Proceedings of a Workshop May 17–18, 1984, Sponsored by the Chemopreventive Branch, Division of Cancer Prevention and Control. Bethesda MD: National Cancer Institute.Google Scholar
Shaheen, Randal M., Mudge, Amy Ralph, and Marcheski, Maura A.. 2014. “FTC Tells L’Oréal That Youth Code Is Not Cracked.” 1 July 2014, www.lexology.com/library/detail.aspx?g=d7b788e5-c8de-4731-aef7–9d907ae0c9f0 (last accessed August 14, 2014).Google Scholar
Sinel'shchikova, T. A., Chekova, V. V., and Zasukhina, G. D.. 1989. “Mekhanizmy narushenii reparatsii DNK v kletkakh cheloveka: Interferon stimuliruet reparativnyi sintez DNK v kletkakh pigmentnoi kserodermy [Mechanisms of impairment of DNA repair in human cells. Interferons stimulated DNA repair in xeroderma pigmentosum cells].” Genetika 25:16581663.Google Scholar
Sloan, Phillip R., and Fogel, D. Brandon, eds. 2011. Creating a Physical Biology: The Three-Man Paper and Early Molecular Biology. Chicago, London: University of Chicago Press.CrossRefGoogle Scholar
Stoff, Heiko. 2012. Wirkstoffe: Eine Wissenschaftsgeschichte der Hormone, Vitamine und Enzyme, 1920–1970. Stuttgart: Steiner.Google Scholar
Stoff, Heiko. 2014. “Zur Kritik der Chemisierung und Technisierung der Umwelt Risiko- und Präventionspolitik von Lebensmittelzusatzstoffen in den 1950er Jahren.” Technikgeschichte 81:253273.CrossRefGoogle Scholar
Stoff, Heiko. 2015. Gift in der Nahrung: Zur Genese der Verbraucherpolitik Mitte des 20. Jahrhunderts. Stuttgart: Steiner.CrossRefGoogle Scholar
Stoff, Heiko, and Schwerin, Alexander. 2014. “Lebensmittelzusatzstoffe: Eine Geschichte gefährlicher Dinge und ihrer Regulierung, 1950–1970.” Technikgeschichte 81:215228.CrossRefGoogle Scholar
Südel, Kirstin M., Venzke, Kirsten, Mielke, Heiko, et al. 2005. “Novel Aspects of Intrinsic and Extrinsic Aging of Human Skin: Beneficial Effects of Soy Extract.” Photochemistry and Photobiology 81:581587.CrossRefGoogle ScholarPubMed
Sullivan, Deborah A. 2001. Cosmetic Surgery: The Cutting Edge of Commercial Medicine in America. New Brunswick NJ: Rutgers University Press.Google Scholar
Tanner, Jakob. 2010. “Lebensmittel und neuzeitliche Technologien des Selbst: Die Inkorporation von Nahrung als Gesundheitsprävention.” In Das präventive Selbst: Eine Kulturgeschichte moderner Gesundheitspolitik, edited by Lengwiler, Martin and Madarász, Jeannette, 3154. Bielefeld: transcript.CrossRefGoogle Scholar
te Hennepe, Mieneke. 2009. “Depicting the Skin: Microsopy and the Visual Articulation of Skin Interior, 1820–1850.” In The Body Within: Art, Medicine and Visualization, edited by van de Vall, Renée and Zwijnenberg, Robert, 5166. Leiden: Brill.Google Scholar
Thoms, Ulrike. 2001. “Die Kategorie Krankheit im Brennpunkt diätetischer Konzepte.” In Essen und Lebensqualität: Natur- und Kulturwissenschaftliche Perspektiven, edited by Neumann, Gerhard, Wierlacher, Alois, and Wild, Rainer, 77106. Frankfurt, New York: Campus.Google Scholar
Turner, Bryan S. 1982. “Government of the Body: Medical Regimens and the Rationalisation of Diet.” British Journal of Sociology 33:254269.CrossRefGoogle Scholar
Walker, J. Samuel. 1994. “The Atomic Energy Commission and the Politics of Radiation Protection, 1967–1971.” ISIS 85:5778.CrossRefGoogle ScholarPubMed
Werner, Petra. 1998. Vitamine als Mythos: Dokumente zur Geschichte der Vitaminforschung. Berlin: Akademie Verlag.Google Scholar
Westermann, Andrea. 2007. Plastik und politische Kultur in Westdeutschland. Zürich: Chronos.CrossRefGoogle Scholar
White, Suzanne Rebecca. 1994. “Chemistry and Controversy: Regulating the Use of Chemicals in Foods, 1883–1959.” Ph.D. diss., Emory University.Google Scholar
WHO Study Group of Diet, Nutrition and Prevention of Noncommunicable Diseases. 1990. Diet, Nutrition, and the Prevention of Chronic Diseases: Report of a WHO Study Group (WHO Technical Report Series, No. 797). Geneva.Google Scholar
Woloshyn, Tania. 2013. “‘Kissed by the Sun’: Tanning the Skin of the Sick with Light Therapeutics, c. 1890–1930.” In A Medical History of Skin: Scratching the Surface, edited by Reinarz, J. and Siena, K., 181194. London: Pickering & Chatto.Google Scholar
Wolstenholme, Gordon E. W., and O’Connor, Maeve, eds. 1969. Mutation as Cellular Process: A Ciba Foundation Symposium. London: Churchill Ltd.CrossRefGoogle Scholar
Yi, Doogab. 2007. “The Coming of Reversibility: The Discovery of DNA Repair between the Atomic Age and the Information Age.” Historical Studies in the Physical and Biological Sciences 37:S:3572.CrossRefGoogle Scholar
Zweiniger-Bargielowska, Ina. 2010. Managing the Body: Beauty, Health, and Fitness in Britain, 1880–1939. New York: Oxford University Press.CrossRefGoogle Scholar