Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-23T15:19:11.662Z Has data issue: false hasContentIssue false
  • English
  • Français

Thermostable vaccines for Newcastle disease: a review

Published online by Cambridge University Press:  13 November 2014

M. SHAHID MAHMOOD ,
F. SIDDIQUE ,
I. HUSSAIN ,
S.I. AHMAD  and
A. RAFIQUE
M. SHAHID MAHMOOD*
Affiliation:
Institute of Microbiology, University of Agriculture, Faisalabad-38040, Pakistan
F. SIDDIQUE
Affiliation:
Institute of Microbiology, University of Agriculture, Faisalabad-38040, Pakistan
I. HUSSAIN
Affiliation:
Institute of Microbiology, University of Agriculture, Faisalabad-38040, Pakistan
S.I. AHMAD
Affiliation:
Institute of Microbiology, University of Agriculture, Faisalabad-38040, Pakistan
A. RAFIQUE
Affiliation:
Department of Zoology, Wildlife and Fisheries, GC University, Faisalabad-38040, Pakistan
*
Corresponding author: shahiduaf@gmail.com
Get access

Abstract

Newcastle Disease (ND) is regarded as one of the major diseases of poultry because of the devastating losses that the virulent form of the ND virus can impose on both commercial and domestic chickens. However, the disease can be controlled through the administration of effective vaccines. Almost all the commercially available ND vaccines require refrigeration and begin to deteriorate rapidly after 1-2 hours if left at room temperature (around 25°C). Subsequently, because maintaining an adequate supply of refrigerated facilities may be a difficult task in many countries with unreliable electrical supplies, the development and large scale production of an effective thermostable ND vaccine seems imperative to support the poultry industry. Such vaccines should be resilient to damage associated with either very cold or hot environments so there are no concerns about the viability of the vaccine in response to temperatures fluctuations that can occur in extreme environments when the difference in temperature during cold and warm seasons can vary greatly. In the following review paper, the development of such a vaccine is discussed, including molecular characterisation, organ tropism of vaccine strains, production, as well as administration methods and their efficacy. It addition, the potential payback has been calculated alongside opportunities provided by removing vaccines from cold chain storage.

Keywords

thermostable vaccinescold chainNewcastle diseasevaccine efficacy
Type
Review Article
Information
World's Poultry Science Journal , Volume 70 , Issue 4 , December 2014 , pp. 829 - 838
Copyright
Copyright © World's Poultry Science Association 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

AGBOR, N.T. (1999) Viability of thermostable Newcastle vaccine (HRV4-UPM) in some Nigerian grains. Thesis for the award of FILMT, Nigeria.Google Scholar
AHMED, T., HOSSAIN, K.M., BILLAH, M.M., ISLAM, K.M.D., AHSAN, M.M. and ISLAM, M.E. (2004) Adaptation of Newcastle Disease virus (NDV) on Vero cell lines. International Journal of Poultry Science 3: 153-156.Google Scholar
ALDERS, R. (2004) Poultry for profit and pleasure. FAO Diversification Booklet 3. Food and Agriculture Organisation of the United Nations: Rome.Google Scholar
ALDERS, G.R. (2005) The Aus AID Southern Africa Newcastle Disease Control Project: its history, approach and lessons Learnt. ACIAR: Village chickens, poverty alleviation and the sustainable control of Newcastle, pp. 62-66.Google Scholar
ALDERS, R.G. and SPRADBROW, P.B. (2001a) SADC planning workshop on Newcastle disease control in village chickens. ACIAR Proceedings No. 103: 170 pp.Google Scholar
ALDERS, R. and SPRADBROW, P. (2001b) Controlling Newcastle Disease in Village Chickens. A Field Manual. ACIAR, Canberra, Australia. pp. 1-70.Google Scholar
ALDERS, R.G., INOUE, S. and KATONGO, J.C. (1994) Prevalence and evaluation of Hitchner B1 and V4 vaccines for the control of Newcastle disease in village chickens in Zambia. Preventive Veterinary Medicine 21: 125-132.Google Scholar
ALDOUS, E.W., MYNN, J.K., BANKS, J. and ALEXANDER, D.J. (2003) A molecular epidemiology study of avian paramyxovirus type 1 (Newcastle disease virus) isolates by phylogenetic analysis of a partial nucleotide sequence of the fusion protein gene. Avian Pathology 32: 237-255.Google Scholar
ALEXANDER, D.J. (2003) Newcastle disease, other paramyxoviruses and pneumovirus infections, in: SAIF, Y.M., BARNES, H.J., GLISSON, J.R., FADLY, A.M., MCDOUGALD, D.J. & SWAYNE, D.E. (Eds) Diseases of Poultry, 11th Ed., pp. 63-100 (Iowa State Press, Ames, IA).Google Scholar
ALEXANDER, D.J. (2009) Newcastle, disease: OIE Terrestrial Manual. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Chapter 2: 3.Google Scholar
ALEXANDER, D.J. and SENNE, D.A. (2008) Newcastle disease and other avian paramyxoviruses, in: DUFOUR, Z.L., SENNE, D.A. & GLISSON, J.R. (Eds) A laboratory manual for the isolation, identification and characterisation of avian pathogens, 5th Ed., pp. 135-141 (Omni Press, Inc, Madison, Wisconsin, USA).Google Scholar
AL-GARIB, S.O., GIELKENS, A.L.J., GRUYS, E. and KOCHI, G. (2003) Review of Newcastle disease virus with particular references to immunity and vaccination. World's Poultry Science Journal 59: 185-200.Google Scholar
ALLAN, W.H. and GOUGH, R.E. (1974) A standard haemagglutination inhibition test for Newcastle disease. I.A. comparison of macro and micro methods. Veterinary Research 95: 120-123.Google Scholar
AMAKYE, A.J., AWUNI, J.A., COLEMAN, T. and SEDOR, V. (2000) Ghanian trials with a rurally produced thermostable Newcastle disease vaccine (strain I-2) in chickens. 26th Animal Science Symposium Ghana Animal Science Association, Kumasi, University of Science and Technology.Google Scholar
ANANTH, A.J., JOHN, K., PRIYADARSHINI, M.L.M. and ALBERT, A. (2008) Isolation of Newcastle Disease Viruses of High Virulence in Unvaccinated Healthy Village Chickens in South India. International Journal of Poultry Science 7: 368-373.Google Scholar
ANON (1991) Websters Newcastle Disease Vaccine for Village Chickens. Castle Hill, Australia, Websters Pty Ltd, Information Dossier.Google Scholar
BELL, J.G., FOTZO, T.M., AMARA, A. and AGBEDE, G. (1995) A field trial of the heat resistant V4 vaccine against Newcastle disease by eye-drop inoculation in village poultry in Cameroon. Preventive Veterinary Medicine 25: 19-25.CrossRefGoogle Scholar
BENSINK, Z. and SPRADBROW, P. (1999) Newcastle disease virus strain I-2; a prospective thermostable vaccine for use in developing countries. Veterinary Microbiology 68: 131-139.Google Scholar
BURLESON, F.G., CHAMBERS, T.M. and WIEDBRAUK, D.L. (1992) Virology: A laboratory manual, Academic press, London, pp: 68-130. ISBN: 0-12-144730-8.Google Scholar
CZEGLEDI, A., UJVÁRI, D., SOMOGYI, E., WEHMANN, E., WERNER, O. and LOMNICZI, B. (2006) Third genome size category of avian paramyxovirus serotype 1 (Newcastle disease virus) and evolutionary implications. Virus Research 120: 36-48.CrossRefGoogle ScholarPubMed
DOYLE, T.M. (1927) A hitherto unrecorded disease of fowls due to a filter-passing virus. Journal of Comparative Pathology 40: 144-169.Google Scholar
ECHEONWU, B.C., NGELE, M.B., ECHEONWU, G.O.N., JOANNIS, T.M., ONOVOH, E.M. and PAUL, G. (2008) Response of chickens to oral vaccination with Newcastle disease virus vaccine strain I-2 coated on maize offal. African Journal of Biotechnology 7: 1594-1599.Google Scholar
FAO (1997) Guidelines for the inclusion of improved household poultry production. Diversification component of the Special Programmed for Food Security.Google Scholar
FOLITSE, R., HALVORSON, D.A. and SIVANANDAN, V. (1988) Efficacy of combined killed-in-oil emulsion and live Newcastle disease vaccines in chickens. Avian Disease 42: 173-178.Google Scholar
FOSTER, H.A., CHITUKUROA, H.R., TUPPAA, T., MWANJALAB, T. and KUSILA, C. (1999) Thermostable newcastle disease vaccines in Tanzania. Veterinary Microbiology 68: 127-130.Google Scholar
GOULD, A.R., HANSSON, E., SELLECK, K., KATTENBELT, J.A., MACKENZIE, M. and DELLA-PORTS, A.J. (2003) Newcastle disease virus fusion and haemagglutinin–neuraminidase gene motifs as markers for viral lineage. Avian Pathology 32: 361-373.Google Scholar
HORIKAMI, S.M., CURRAN, J., KOLAKOFSKY, D. and MOYER, S.A. (1992) Complexes of Sendai virus NP–P and P–L proteins are required for defective interfering particle genome replication in vitro. Journal of Virology 66: 4901-4908.Google Scholar
ILLANGO, J., OLAHO-MUKANI, W., MUKIIBI-MUKA, G., ABILA, P.P. and ETOORI, A. (2005) Immunogenicity of a locally produced Newcastle Disease I-2 Thermostable vaccine in Chicken in Uganda. Tropical Animal Health and Production 37: 25-31.Google Scholar
ILLANGO, J., MUKIIBI, M.G., ABILA, P.P., MUSISI, G. and ETOORI, A. (2008) The value of the Newcastle disease I-2 thermostable vaccine use in the rural free-range poultry management system in Uganda. Livestock Research for Rural Development 20: 9-13.Google Scholar
IROEGBU, C.U. and NCHINDA, G.W. (1999) Evaluation of cassava feed for oral delivery of ND V4 vaccine. Bulletin Animal Production African 47: 155-161.Google Scholar
JAYAWARDANE, G.W.L. and SPRADBROW, P.B. (1995a) Cell-mediated immunity in chickens vaccinated with the V4 strain of Newcastle disease virus. Veterinary Microbiology 46: 37-41.Google Scholar
JAYAWARDANE, G.W.L. and SPRADBROW, P.B. (1995b) Mucosal immunity in chickens vaccinated with V4 strain of Newcastle disease virus. Veterinary Microbiology 46: 69-77.Google Scholar
KALTHOFF, D., BREITHAUPT, A., TEIFKE, J.P., GLOBIG, A., HARDER, T., METTENLEITER, T.C. and BEER, M. (2008) Highly Pathogenic Avian Influenza virus (H5N1) in experimentally infected adult Mute Swans. Emerging Infectious Diseases 14: 1267-1270.Google Scholar
KAPCZYNSKI, D.R. and KING, D.J. (2005) Protection of chickens against overt clinical disease and determination of viral shedding foll. Vaccination with commercially available Newcastle disease virus vaccines upon challenge with highly virulent virus from the California 2002 exotic ND outbreak. Vaccine 23: 3424-3433.Google Scholar
KATTENBELT, J.A., STEVENS, M.P. and GOULD, A.R. (2006) Sequence variation in the Newcastle disease virus genome. Virus Research 116: 168-184.Google Scholar
KOMBA, E.V.G., MBYUZI, A.O. and MULANGILA, R.C.T. (2012) Adoption of I2 vaccine in immunization of village chickens against Newcastle disease virus in Southern Tanzania: Immune status of farmer vaccinated birds. Journal of Agricultural Science 4 (4): 23-28.Google Scholar
MADHAN, C., MOHAN, D.S. and KUMANAN, K. (2005) Molecular changes of the fusion protein Gene of chicken embryo fibroblast adapted velogenic Newcastle disease virus: Effect on its pathogenicity. Avian Diseases 49: 56-62.Google Scholar
MGOMEZULU, R.A., ALDERS, R.G., CHIKUNGWA, P.B., YOUNG, M.P., LIPITAL, W.G. and WANDAL, G.W. (2009) Trials with a thermotolerant 1-2 Newcastle disease vaccine in confined Australorp chickens and scavenging village chickens in Malawi.Google Scholar
MILLER, P.J., DECANINI, E.L. and AFONSO, C.L. (2010) Newcastle disease: Evolution of genotypes and the related diagnostic challenges. Infection Genetics and Evolution 10: 26-35.Google Scholar
MOHAMED, M.H., KUMAR, S., PALDURAI, A., MEGAHED, M.M., GHANEM, I.A., LEBDAH, M.A. and SAMAL, S.K. (2012) Complete genome sequence of a virulent Newcastle disease virus isolated from an outbreak in chickens in Egypt. Virus Genetics 39: 234-237.Google Scholar
MOHAN, C.M., DEY, S., KUMANAN, K., MAHOHAR, B.M. and NAINAR, A.M. (2007) Adaptation of a velogenic disease virus to Vero cells: assessing the molecular changes before and after infection. Veterinary Research Communication 31: 371-383.Google Scholar
MORGAN, R.W., GELB, J., POPE, C.R. and SONDERMEIJER, P.J. (1993) Efficacy in chickens of a herpes virus of turkey's recombinant vaccine containing the fusion gene of Newcastle disease virus: onset of protection and effect of maternal antibodies. Avian Diseases 37: 1032-1040.Google Scholar
MSOFFE, P.L.M., BUNN, D., MUHAIRWA, A.P., MTAMBO, M.M.A., MWAMHEHE, H., MSAGO, A., MLOZI, M.R.S. and CARDONA, C.J. (2010) Implementing poultry vaccination and biosecurity at the village level in Tanzania: a social strategy to promote health in free-range poultry populations. Tropical Animal Health and Production 42: 253-263.Google Scholar
MUSA, U., ABDU, P.A., MERA, U.M., EMMENNA, P.E. and AHMED, M.S. (2010) Vaccination with Newcastle Disease Vaccines Strain I-2 and Lasota In Commercial And Local Chickens In Plateau State Nigeria. Nigerian Veterinary Journal 31: 46-55.Google Scholar
NAWANTA, J.A., ABDU, P.A. and EZEMA, W.S. (2008) Epidemiology, challenges and prospects for control of Newcastle disease in village poultry in Nigeria. World's Poultry Science Journal 64: 119-127.Google Scholar
NEGA, M., MOGES, F., MAZENGIA, H., ZELEKE, G. and TAMIR, T. (2011) Evaluation of I-2 Thermostable Newcastle Disease Vaccine On Local Chickens In Selected Districts Of Western Amhara. Online Journal of Animal and Feed Research 3: 244-248.Google Scholar
NSSIEN, M.A.S. and ADENE, D.F. (2002) Thermostability of Reconstituted Newcastle Disease Virus Strains At 36°C Temperature. African Journal of Biomedical Research 5: 87-89.Google Scholar
OIE (2000) Newcastle Disease. In: Manual of Standard for Diagnostic Tests and Vaccines.5th edition, Paris, Pp. 104-124.Google Scholar
OIE (2012) Newcastle disease. Manual of standard for diagnostic tests and vaccines. Office International des Epizootics, Paris. pp. 221 -232.Google Scholar
OLABODE, A.O., NDAKO, J.A., ECHEONWU, G., NWANKITI, O.O. and CHUKWUEDO, A.A. (2010) Use of cracked maize as a carrier for NDV4 vaccine in experimental vaccination of chickens. Virology Journal 7: 67-70.Google Scholar
PALYA, V., KISS, I., TATAR, K.T., MATO, T., FELFOLDI, B. and GARDIN, Y. (2012) Advancement in vaccination against Newcastle disease: recombinant HVT NDV provides high clinical protection and reduces challenge virus shedding with the absence of vaccine reactions. Avian Disease 56: 282-287.CrossRefGoogle ScholarPubMed
RAGAVAN, V.S.K., KUMARAN, K. and NACHIMUTHU, K. (1998) Use of MDBK cells in characterising Newcastle disease virus isolates in desi chickens. Indian Veterinary Journal 75: 1079-1082.Google Scholar
RAHMAN, M.B., RAHMAN, M.M., RAHMAN, M., KABIR, S.M.L., NAZIR, K.H.M.N.H. and AMIN, M.M. (2004) Efficiency of V4 HR Newcastle disease (V4HR-ND) vaccine in Broiler Birds in Bangladesh. International Journal of Poultry Science 5: 365-368.Google Scholar
REHMANI, S.F. and SPRADBROW, P.B. (1995) Receptors for the V4 strain of Newcastle disease virus in the digestive tract of chickens. Veterinary Microbiology 46: 43-46.Google Scholar
SAIFUDDIN, M., SARKER, A.J.S., AMIN, M.M. and RAHMAN, M.A. (1986) Studies on the efficacy of Newcastle disease vaccines and their vaccination schedule. Bangladesh Veterinary Journal 20: 67-75.Google Scholar
SAMUEL, J.L. and SPRADBROW, P.B. (1991) Selective oral vaccination against Newcastle disease by creep feeding young chicks in open-range poultry flock. Preventive Veterinary Medicine 10: 273-282.Google Scholar
SIMMONS, G.C. (1967) Isolation of Newcastle disease virus in Queensland. Australian workshop training 43: 29-30.Google Scholar
SPRADBROW, P.B. (1992a) A review of the use of food carriers for the delivery of oral Newcastle disease vaccine, in: SPRADBROW, P.B. (Ed.) Newcastle Disease in Village Chickens Control with Thermostable Oral Vaccine, No. 39. pp: 18-20 (Australian Centre for International Agricultural Research).Google Scholar
SPRADBROW, P.B. (1992b) Newcastle disease in village chickens. Control with thermostable oral vaccine. Proceeding International Workshop Kuala-Lumpur, Malaysia.Google Scholar
SPRADBROW, P.B. (1993/94) : Newcastle disease in rural chickens. Poultry Science Review 5: 57-96.Google Scholar
SPRADBROW, P.B., MACKENZIE, M. and GRIMES, S.E. (1995) Recent isolates of Newcastle disease virus in Australia. Veterinary Microbiology 46: 21-28.Google Scholar
TU, T.D., PHUC, K.V., DIHN, N.T.K., QUOC, D.N. and SPRADBROW, P.B. (1998) Vietnamese trials with a thermostable Newcastle disease vaccine (Strain I-2) in experimental and village chickens. Preventive Veterinary Medicine 34: 205-214.Google Scholar
WAMBURA, P.N. (2003) Thermostable I-2 strain of Newcastle disease virus as a rural vaccine. PhD thesis, University of Queensland, Australia.Google Scholar
WAMBURA, P.N. (2006) Comparative Propagation of Newcastle disease virus (Strains I-2 and V4) on Chicken Embryo Tracheal Explants. Veterinary Research Communications 30: 673-677.Google Scholar
WAMBURA, P.N. (2009) Oral vaccination of chickens against Newcastle disease with I-2 vaccine coated on oiled rice. Tropical Animal Health and Production 41: 205-208.CrossRefGoogle ScholarPubMed
WAMBURA, P.N. (2011) Formulation of novel nano-encapsulated Newcastle disease vaccine tablets for vaccination of village chickens. Tropical Animal Health Production 43: 165-169.Google Scholar
WAMBURA, P.N., KAPAGA, A.M. and HYERA, J.M.K. (2000) Experimental trials with a thermostable Newcastle disease virus (strain I2) in commercial and village chickens in Tanzania. Preventive Veterinary Medicine 43: 75-83.Google Scholar
WAMBURA, P.N., MASAMBU, J. and MSAMI, H. (2006a) Molecular diagnosis and epidemiology of African swine fever outbreaks in Tanzania. Veterinary Research Communications 30: 667-672.Google Scholar
WAMBURA, P.N., MEERS, J. and SPRADBROW, P.B. (2001) Deduced amino acid sequence surrounding the fusion glycoprotein cleavage site of the avirulent thermostable vaccine strain I-2 of Newcastle disease virus. Third Australian Veterinary Virology Conference, Sydney, Australia.Google Scholar
WAMBURA, P.N., MEERS, J. and SPRADBROW, P.B. (2006b) Determination of Organ Tropism of Newcastle Disease Virus (Strain I-2) by Virus Isolation and Reverse Transcription-Polymerase Chain Reaction. Veterinary Research Communications 30: 697-706.Google Scholar
WAMBURA, P.N., MEERS, J. and SPRADBROW, P. (2007) Survival of avirulent thermostable Newcastle disease virus (strain I-2) in raw, baked, oiled, and cooked white rice at ambient temperatures. Journal of Veterinary Science 8: 303-305.Google Scholar
XIAO, S., PALDURAI, A., NAYAK, B., SAMUEL, A., BHAROTO, E.E., PRAJITNO, T.Y., COLLINS, P.L. and SAMAL, S.K. (2012) Complete genome sequences of Newcastle disease virus strains circulating in chicken populations of Indonesia. Journal of Virology 86: 5969-5970.Google Scholar
YOKOYAMA, N., MAEDA, K. and MIKAMI, T. (1997) Recombinant viral vector vaccines for the veterinary use. Journal of Veterinary Medicine and Science 59: 311-322.CrossRefGoogle ScholarPubMed
YOUNG, M. and ALDERS, R. (2002) Controlling Newcastle Disease in village chickens: laboratory manual. ACIAR.Google Scholar
YUSOFF, K., TAN, W.S., LAU, C.H., NG, B.K. and IBRAHIM, A.L. (1996) Sequence of the haemagglutinin-neuraminidase gene of the Newcastle disease virus oral vaccine strain V4 (UPM). Avian Pathology 25: 837-844.Google Scholar
ZOTH, S.C., GOMEZ, E., CARRILLO, E. and BERNSTEIN, A. (2008) locally produced mucosal IgG in chickens immunised with conventional vaccines for Newcastle disease virus. Brazilian Journal of Medical and Biological Research 41: 318-323.Google Scholar