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Presentation and initial assessment of ENT problems in patients with granulomatosis with polyangiitis (Wegener's)

Published online by Cambridge University Press:  22 July 2014

M Martinez Del Pero ,
D McKiernan  and
P Jani
M Martinez Del Pero*
Affiliation:
Department of Otolaryngology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK
D McKiernan
Affiliation:
Department of Otolaryngology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK
P Jani
Affiliation:
Department of Otolaryngology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK
*
Address for correspondence: Mr M Martinez Del Pero, ENT Department, Box 48, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK E-mail: marcos@doctors.org.uk
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Abstract

Background:

Granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) is a primary systemic vasculitis that affects medium to small sized vessels throughout the body. It often presents with symptoms and signs involving the ear, nose, and head and neck area.

Objective:

To highlight salient features of ENT-related issues in granulomatosis with polyangiitis, and raise awareness of the condition.

Methods:

A case report of a patient with limited disease and an insidious onset is presented, along with a review of the current literature. In addition, basic initial management is described.

Results:

Eighty-six publications were used to describe salient features of ENT-related issues in granulomatosis with polyangiitis.

Conclusion:

The time to diagnosis has not reduced significantly in the last 10 years in the UK. A high index of suspicion is required for an earlier diagnosis of granulomatosis with polyangiitis.

Keywords

Wegener GranulomatosisVasculitisAntibodies, Antineutrophil CytoplasmicDiagnosis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 8 , August 2014 , pp. 730 - 737
Copyright
Copyright © JLO (1984) Limited 2014 

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