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VAGINAL MICROBIOME–PREGNANT HOST INTERACTIONS DETERMINE A SIGNIFICANT PROPORTION OF PRETERM LABOUR

Published online by Cambridge University Press:  22 May 2014

MANJU CHANDIRAMANI ,
PHILLIP R BENNETT ,
RICHARD BROWN ,
YUN S LEE  and
DAVID A. MACINTYRE
MANJU CHANDIRAMANI*
Affiliation:
Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
PHILLIP R BENNETT
Affiliation:
Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
RICHARD BROWN
Affiliation:
Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
YUN S LEE
Affiliation:
Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
DAVID A. MACINTYRE*
Affiliation:
Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
*
Dr Manju Chandiramani and Dr David MacIntyre, Institute of Reproductive & Developmental Biology, Imperial College London, London W12 ONN, United Kingdom. Email addresses: m.chandiramani@imperial.ac.uk; d.macintyre@imperial.ac.uk.
Dr Manju Chandiramani and Dr David MacIntyre, Institute of Reproductive & Developmental Biology, Imperial College London, London W12 ONN, United Kingdom. Email addresses: m.chandiramani@imperial.ac.uk; d.macintyre@imperial.ac.uk.
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Extract

Preterm birth (PTB) has a global prevalence of 11.1% accounting for almost 15 million babies born each year before 37 weeks of gestation. It is a risk factor in over 50% of all neonatal deaths, which amounts to 1.1 million deaths annually. Preterm birth, especially at early gestational ages is associated with a high risk of long-term morbidity in survivors. Despite much research effort, PTB rates continue to rise, placing immense financial and emotional burden on society. In the US, the annual societal economic cost associated with PTB is $26.2 billion with an average of $51,600 being spent per infant born preterm. Preterm labour (PTL) accounts for 70% of these births, of which 25% are preceded by preterm pre-labour rupture of membranes (PPROM).

Type
Hypotheses
Information
Fetal and Maternal Medicine Review , Volume 25 , Issue 1 , February 2014 , pp. 73 - 78
Copyright
Copyright © Cambridge University Press 2014 

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References

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