Epidemiology and Infection

Original Papers

Veterinary/Zoonoses

Evolutionary history of Ebola virus

Y. H. LIa1 and S. P. CHENa2 c1

a1 Center of Hematopoietic Stem Cell Transplantation, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing, PR China

a2 Department of Laboratory Medicine, Affiliated Hospital of the Academy of Military Medical Sciences, Beijing, PR China

SUMMARY

Since Ebola virus was discovered in 1970s, the virus has persisted in Africa and sporadic fatal outbreaks in humans and non-human primates have been reported. However, the evolutionary history of Ebola virus remains unclear. In this study, 27 Ebola virus strains with complete glycoprotein genes, including five species (Zaire, Sudan, Reston, Tai Forest, Bundibugyo), were analysed. Here, we propose a hypothesis of the evolutionary history of Ebola virus which will be helpful to investigate the molecular evolution of these viruses.

(Received May 06 2013)

(Revised August 08 2013)

(Accepted August 16 2013)

(Online publication September 16 2013)

Key word

  • Molecular epidemiology

Correspondence

c1 Author for correspondence: Dr S. P. Chen, Department of Laboratory Medicine, Affiliated Hospital of the Academy of Military Medical Sciences, No. 8, Dongdajie Street, Fengtai District, Beijing 100071, PR China. (Email: shpchen@hotmail.com)

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