CNS Spectrums

Brainstorms

Long-acting injectable antipsychotics: shall the last be first?

Stephen M. Stahl

Abstract

ISSUE:A paradigm shift is afoot in which the “last shall be first,” namely, use of long-acting injectable (LAI) antipsychotics, rather than being reserved for use only at the last stages of schizophrenia, may be shifting to first-line treatment of early episodes of this illness.

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