British Journal of Nutrition

Research Article

Emerging diet-related surrogate end points for colorectal cancer: UK Food Standards Agency diet and colonic health workshop report

Peter Sandersona1 c1, Ian T. Johnsona2, John C. Mathersa3, Hilary J. Powersa4, C. Stephen Downesa5, Angela P. McGlynna5, Rae Darea5, Ellen Kampmana6, Beatrice L. Pool-Zobela7, Sheila A. Binghama8 and Joseph J. Raftera9

a1 Nutrition Division, Food Standards Agency, London, UK

a2 Intestinal Health and Function Group, Institute of Food Research, Norwich, UK

a3 Human Nutrition Research Centre, University of Newcastle, UK

a4 The Centre for Human Nutrition, University of Sheffield, UK

a5 School of Biomedical Sciences, University of Ulster, Coleraine, UK

a6 Division of Human Nutrition and Epidemiology, Wageningen University, The Netherlands

a7 Friedrich-Schiller-University of Jena, Institute for Nutrition and Nutritional Toxicology, Jena, Germany

a8 MRC Dunn Human Nutrition Unit, Cambridge, UK

a9 Department of Medical Nutrition, Karolinska Institute, Huddinge, Sweden

Abstract

The UK Food Standards Agency convened a group of expert scientists to review current research investigating emerging diet-related surrogate end points for colorectal cancer (CRC). The workshop aimed to overview current research and establish priorities for future research. The workshop considered that the validation of current putative diet-related surrogate end points for CRC and the development of novel ones, particularly in the emerging fields of proteomics, genomics and epigenomics, should be a high priority for future research.

(Received September 03 2003)

(Accepted September 29 2003)

Correspondence:

c1 *Corresponding author: Dr Peter Sanderson, fax +44 20 7276 8906, email peter.sanderson@foodstandards.gsi.gov.uk