The Journal of Laryngology & Otology

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Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

A Eftekhariana1 c1, H Moghaddasia1, L Gachkara2 and S S A Amlashia1

a1 Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

a2 Department of Infectious Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Objective: To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients.

Methods: This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test.

Results: All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients).

Conclusion: Cerumen can be a potential source of transmission of hepatitis B virus.

(Accepted February 19 2013)

(Online publication October 17 2013)

Key words

  • Hepatitis B Virus;
  • Cerumen;
  • Chronic Hepatitis

Correspondence

c1 Address for correspondence: Dr A Eftekharian, Department of Otorhinolaryngology, Loghman Hospital, Kamali Ave, Kargar, 13336-31151 Tehran, Iran Fax: +98,-21-55416170 E-mail: alishko@gmail.com

Footnotes

  Dr A Eftekharian takes responsibility for the integrity of the content of the paper

Competing interests: None declared

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