Epidemiology and Infection

  • Epidemiology and Infection / Volume 141 / Issue 08 / August 2013, pp 1604-1613
  • Copyright © Cambridge University Press 2012 The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike licence <http://creativecommons.org/licenses/by-nc-sa/2.5/>. The written permission of Cambridge University Press must be obtained for commercial re-use.
  • DOI: http://dx.doi.org/10.1017/S0950268812002014 (About DOI), Published online: 25 September 2012
  • OPEN ACCESS

Original Papers

Other gastroenteritis

Epidemiological features and risk factors of Salmonella gastroenteritis in children resident in Ho Chi Minh City, Vietnam

C. N. THOMPSONa1a2, V. T. M. PHANa2, T. P. T. LEa2, T. N. T. PHAMa3, L. P. HOANGa4, V. HAa5, V. M. H. NGUYENa2, V. M. PHAMa2, T. V. NGUYENa2, T. T. CAOa2, T. T. N. TRANa2, T. T. H. NGUYENa3, M. T. DAOa6, J. I. CAMPBELLa1a2, T. C. NGUYENa5, C. T. TANGa5, M. T. HAa4, J. FARRARa1a2 and S. BAKERa1a2 c1

a1 Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, UK

a2 Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam

a3 Children's Hospital 2, Ho Chi Minh City, Vietnam

a4 Children's Hospital 1, Ho Chi Minh City, Vietnam

a5 Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

a6 Geomatics Center, Vietnam National University, Ho Chi Minh City, Vietnam

SUMMARY

Non-typhoidal Salmonella are an important but poorly characterized cause of paediatric diarrhoea in developing countries. We conducted a hospital-based case-control study in children aged <5 years in Ho Chi Minh City to define the epidemiology and examine risk factors associated with Salmonella diarrhoeal infections. From 1419 diarrhoea cases and 571 controls enrolled between 2009 and 2010, 77 (5·4%) diarrhoea cases were stool culture-positive for non-typhoidal Salmonella. Salmonella patients were more likely to be younger than controls (median age 10 and 12 months, respectively) [odds ratio (OR) 0·97; 95% confidence interval (CI) 0·94–0·99], to report a recent diarrhoeal contact (8·1% cases, 1·8% controls; OR 5·98, 95% CI 1·8–20·4) and to live in a household with >2 children (cases 20·8%, controls 10·2%; OR 2·32, 95% CI 1·2–4·7). Our findings indicate that Salmonella are an important cause of paediatric gastroenteritis in this setting and we suggest that transmission may occur through direct human contact in the home.

(Received December 21 2011)

(Revised July 12 2012)

(Accepted August 13 2012)

(Online publication September 25 2012)

Key words

  • Bacterial infections;
  • epidemiology;
  • paediatrics;
  • Salmonella

Correspondence

c1 Author for correspondence: Dr S. Baker, Enteric Infections Group, Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 764 Vo Van Kiet, District 5, Ho Chi Minh City, Vietnam. (Email: sbaker@oucru.org)

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