Epidemiology and Infection

Original Papers

Gastrointestinal infection

Rotavirus genotypes in children in the Basque Country (North of Spain): rapid and intense emergence of the G12[P8] genotype

G. CILLAa1 c1, M. MONTESa1, M. GOMARIZa1, M. ALKORTAa2, A. ITURZAETAa2, E. G. PEREZ-YARZAa3a4 and E. PEREZ-TRALLEROa1a4

a1 Servicio de Microbiología, Hospital Universitario Donostia-Instituto BioDonostia, San Sebastián, Spain

a2 Servicio de Microbiología, Hospital Zumarraga, Zumarraga, Spain

a3 Servicio de Pediatría, Hospital Universitario Donostia, San Sebastián, Spain

a4 Facultad de Medicina, Basque Country University UPV/EHU, San Sebastián, Spain

SUMMARY

Between July 2009 and June 2011, rotavirus was detected in 507 of 4597 episodes of acute gastroenteritis in children aged <3 years in Gipuzkoa (Basque Country, Spain), of which the G-type was determined in 458 (90·3%). During the annual seasonal epidemic of 2010–2011, the unusual G-type 12 was predominant, causing 65% (145/223) of cases of rotavirus gastroenteritis. All the G12 strains were clustered in lineage III and were preferentially associated with P-type 8. This epidemic was characterized by broad geographical distribution (rural and urban) and, over 7 months, affected both infants and children, the most frequently affected being children between 4 and 24 months. Of children with rotavirus G12, 16% required hospital admission, the admission rate in children aged <2 years being 20·7 cases/10 000 children. The sudden emergence and predominance of G12 rotaviruses documented in this winter outbreak suggest that they may soon become a major human rotavirus genotype.

(Received February 22 2012)

(Revised May 03 2012)

(Accepted May 30 2012)

(Online publication July 03 2012)

Key words

  • Epidemic;
  • genotypes;
  • rotavirus;
  • rotavirus G12;
  • rotavirus surveillance

Correspondence

c1 Author for correspondence: Dr G. Cilla, Servicio de Microbiología, Hospital Universitario Donostia, Paseo Dr. Beguiristain s/n, 20014 San Sebastián, Spain. (Email: gustavo.cillaeguiluz@osakidetza.net).

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