a1 Qingdao Centers for Disease Control and Prevention, Qingdao, China
a2 Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland
a3 Department of Public Health, Qingdao University Medical College, Qingdao, China
a4 Jiaonan Centers for Disease Control and Prevention, Qingdao, China
a5 Epidemiology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
a6 Department of Clinical Genetics, Odense University Hospital, Odense, Denmark
a7 Department of Public Health, University of Shandong, Jinan, China
In 1998, the Qingdao Twin Registry was initiated as the main part of the Chinese National Twin Registry. By 2005, a total of 10,655 twin pairs had been recruited. Since then new twin cohorts have been sampled, with one longitudinal cohort of adolescent twins selected to explore determinants of metabolic disorders and health behaviors during puberty and young adulthood. Adult twins have been sampled for studying heritability of multiple phenotypes associated with metabolic disorders. In addition, an elderly twin cohort has been recruited with a focus on genetic studies of aging-related phenotypes using twin modeling and genome-wide association analysis. Cross-cultural collaborative studies have been carried out between China, Denmark, Finland, and US cohorts. Ongoing data collection and analysis for the Qingdao Twin Registry will be discussed in this article.
(Received August 31 2012)
(Accepted October 17 2012)
(Online publication November 27 2012)
* These authors contributed equally.