British Journal of Nutrition

Full Papers

Human and Clinical Nutrition

Dietary inclusion of salmon, herring and pompano as oily fish reduces CVD risk markers in dyslipidaemic middle-aged and elderly Chinese women

Jian Zhanga1a2a3, Chunrong Wanga1, Lixiang Lia1, Qingqing Mana1, Liping Menga1, Pengkun Songa1, Livar Frøylanda2 and Zhen-Yu Dua2 c1

a1 Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100050, People's Republic of China

a2 National Institute of Nutrition and Seafood Research (NIFES), N-5817 Bergen, Norway

a3 Department of Biomedicine, University of Bergen, Bergen, Norway

Abstract

Dietary intervention studies to assess the cardioprotective effects of oily fish are scarce in China. The present study aimed to examine the effects of the oily fish, Norwegian salmon, herring and local farmed pompano (Trachinotus ovatus) on CVD risk markers when included in the Chinese diet. In this 8-week, parallel-arm, randomised intervention study, 126 Chinese women with hypertriacylglycerolaemia, aged 35–70 years, were assigned to four groups to consume an experimental lunch containing 80 g fillets of either one of three oily fish or a mix of commonly eaten meats (pork/chicken/beef/lean fish) for 5 d/week. The results showed that inclusion of the three oily fish significantly increased the intake of n-3 long-chain PUFA (LC-PUFA) while decreasing the dietary n-6:n-3 PUFA ratio. Compared to the control group, significant increases of DHA, EPA+DHA and total n-3 PUFA in plasma choline phosphoglyceride were observed in the three oily fish groups. Plasma TAG levels were significantly reduced only in the salmon and herring groups. When compared to the baseline level, the three oily fish diets significantly decreased serum concentrations of TAG, apoB, apoCII and apoCIII, but only the salmon and herring diets significantly lowered TNF-α and raised adiponectin levels in serum. The salmon diet additionally decreased the serum concentration of IL-6. To conclude, dietary inclusion of salmon, herring and pompano as oily fish can effectively increase serum n-3 LC-PUFA content and are associated with favourable biochemical changes in dyslipidaemic middle-aged and elderly Chinese women, and these beneficial effects are mainly associated with n-3 LC-PUFA contents.

(Received April 10 2011)

(Revised November 16 2011)

(Accepted November 16 2011)

(Online publication January 06 2012)

Key Words:

  • Dietary intervention study;
  • Oily fish;
  • Salmon;
  • Herring;
  • Pompano;
  • n-3 Fatty acids;
  • CVD biomarkers

Correspondence:

c1 Corresponding author: Dr Z.-Y. Du, fax +47 55905299, email zdu@nifes.no

Footnotes

  Abbreviations: AA, arachidonic acid; CPG, choline phosphoglyceride; HDL-C, HDL-cholesterol; LC-PUFA, long-chain PUFA; LDL-C, LDL-cholesterol; TC, total cholesterol

0Comments