British Journal of Nutrition

Table of Contents - 1992 - Volume 67, Issue 02  

Diurnal Effects in Metabolism

The effect of malnutrition on insulin binding to rat erythrocytes

Hazel M. Payne-Robinsona1 and Richard Browna2

a1 Tropical Metabolism Research Unit, University of the West Indies, Kingston 7, Jamaica

a2 Department of Medical Biochemistry, Welsh National School of Medicine, Cardiff

Abstract

Insulin binding to erythrocyte receptors was compared in malnourished and control rats. Percentage specific insulin binding to malnourished rat erythrocytes was significantly lower than to control erythrocytes (P < 0.001). The low insulin binding in the malnourished rat erythrocytes was accompanied by low insulin receptor affinity (P = 0.035).

(Received August 23 1990)

(Accepted May 08 1991)

Keywords

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