Cambridge Journals Online

Research Article

Assessment of adipose tissue distribution by computed axial tomography in obese women: association with body density and anthropometric measurements

Mario Ferlanda1, Jean-pierre DesprÉSa1*, Angelo Tremblaya1, Sylvie Pinaulta3, AndrÉ Nadeaua2, Sital Moorjania4, Paul J. Lupiena4, Germain ThÉriaulta1 and Claude Boucharda1 a1 Physical Activity Sciences Laboratory a2 Department of Medicine a3 Department of Radiology a4 Lipid Research Unit, Lava1 University, Ste-Foy, Quebec, GIK 7P4, Canada

Article author query ferland m   després j   tremblay a   pinault s   nadeau a   moorjani s   lupien pj   thériault g   bouchard c

Abstract

1. Abdominal obesity is associated with numerous metabolic complications. Deep abdominal adipose tissue is critical in the association between the level of abdominal obesity and cardiovascular risk factors.

2. Adipose tissue localization was assessed by computed axial tomography (CAT), and its association with body density and anthropometric measurements was investigated in a sample of fifty-one obese women (percentage body fat 45·9 (SD 5·6)) aged 35·7 (SD 5·5) years. The CAT scans were performed at three levels: lower chest, abdomen and mid-thigh.

3. The total adipose tissue volume computed from these three scans was highly correlated with body fat mass (r 0·94, P < 0·001). The proportion of deep abdominal fat as measured by the ratio of deep: total adipose tissue areas at the abdominal level was not significantly correlated with body fat mass, but it was moderately associated with the ratio of waist: hip circumferences (WHR) (r 0·49, P < 0·001). The absolute amount of deep abdominal fat was, however, significantly correlated with body fat mass (r 0·72, P < 0·001).

4. The subscapular (r 0·38) and the abdominal (r 0·38) skinfolds were the only two skinfolds that were significantly associated with the proportion of deep abdominal fat (P < 0·01). These skinfolds were also those which showed the highest correlation with the absolute amount of deep abdominal fat (r 0·65, P < 0·001, for both skinfolds).

5. A three-site CAT-scan procedure can be used for the estimation of body fat mass in premenopausal obese women.

6. In these obese women, there was no significant association between total adiposity and the proportion of deep adipose tissue at the abdominal level.

7. In premenopausal obese women, the absolute amount of deep abdominal fat can be predicted from anthropometric measurements with more accuracy than the relative amount of deep abdominal fat.

(Received August 12 1988)

(Accepted October 06 1988)

Footnotes

* For reprints.