The Journal of Laryngology & Otology

Table of Contents - June 2012 - Volume 126, Issue 06  

Clinical Records

Coexistence of rhinoscleroma with Rosai–Dorfman disease: is rhinoscleroma a cause of this disease?

J O Kumaria1 c1

a1 Department of ENT, Co-Operative Medical College, Kochi, Kerala, India

Abstract

Introduction: Rhinoscleroma and Rosai–Dorfman disease have been reported to coexist in the same patient at different sites. Rosai–Dorfman disease may have an aetiological relationship with rhinoscleroma, although this has not yet been proved.

Case report: A case of a 42-year-old woman with recurrent nasal masses is presented, with histopathological proof of both conditions coexisting in the same nasal lesion.

Discussion: The aetiopathology, clinical features and treatment of both diseases are discussed and a literature survey is reported. Histologically, the presence of Mikulicz cells with entrapped, rod-like, Gram-negative bacilli and Russell bodies suggests rhinoscleroma. Emperipolesis and S-100-positive histiocytes confirm the diagnosis of Rosai-Dorfman disease. The presence of both in the same slides from affected tissues has never been demonstrated before. In the light of this evidence, the author believes that rhinoscleroma must be considered in the aetiology of Rosai–Dorfman disease.

(Accepted August 24 2011)

(Online publication April 19 2012)

Key words

Correspondence:

c1 Address for correspondence: Dr Jyothy O Kumari, Saradapadmam, Mamala PO, Ernakulam Dist, Kerala, India PIN 682305 E-mail: joku44@yahoo.co.in

Footnotes

Dr J O Kumari takes responsibility for the integrity of the content of the paper

Competing interests: None declared

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