CNS Spectrums

Review Article

Practical guide for prescribing MAOIs: debunking myths and removing barriers

Meghan M. Gradya1 c1 and Stephen M. Stahla1a2a3

a1 Neuroscience Education Institute, Carlsbad, California, USA

a2 Department of Psychiatry, University of California–San Diego, San Diego, California, USA

a3 Department of Psychiatry, University of Cambridge, Cambridge, UK

Abstract

Despite the fact that monoamine oxidase inhibitors (MAOIs) can be highly effective therapeutic agents for depression and some anxiety disorders, they tend to be underutilized in clinical practice. This is due at least in part to the fact that there is a great deal of misinformation and mythology about their dietary and drug interactions. This article is intended to serve as a guide for clinicians who are not particularly familiar with MAO inhibitors; its aim is to help these clinicians competently integrate these agents into clinical practice when appropriate.

(Received January 15 2012)

(Accepted February 06 2012)

Key words

  • Depression;
  • interaction;
  • MAOI;
  • monoamine oxidase

Correspondence:

c1 Address for correspondence: Meghan M. Grady, BA, Director, Content Development, Neuroscience Education Institute. 1930 Palomar Point Way, Ste 101, Carlsbad, CA 92008 Email mgrady@neiglobal.com

Footnotes

The activity is supported by an educational grant from Dey Pharma, L.P.

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