Epidemiology and Psychiatric Sciences

Neurobiology of Psychosis

The dysregulation profile in children and adolescents: a potential index for major psychopathology?

M. Bellania1 c1, G. A. L. Negria2 and P. Brambillaa2a3

a1 Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, Inter-University Center for Behavioural Neurosciences (ICBN), University of Verona, Verona, Italy

a2 Department of Experimental Clinical Medicine, Inter-University Center for Behavioural Neurosciences (ICBN), University of Udine, Udine, Italy

a3 IRCCS ‘E. Medea’ Scientific Institute, Udine, Italy

We here review the literature on Child Behaviour Checklist-Dysregulation Profile (CBCL-DP) index, which potentially represents a developmental profile of major psychopathology in early adulthood. The understanding of the neural underpinnings of children and adolescents with altered regulation of affect and behaviour may ultimately help in planning strategies to prevent psychiatric syndromes during development.

(Received November 30 2011)

(Revised December 12 2011)

(Accepted December 13 2011)

Correspondence:

c1 Address for correspondence: Dr M. Bellani, Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy. (Email: marcella.bellani@univr.it, paolo.brambilla@uniud.it)

Footnotes

This Section of Epidemiology and Psychiatric Sciences regularly appears in each issue of the Journal to describe relevant studies investigating the relationship between neurobiology and psychosocial psychiatry in major psychoses. The aim of these Editorials is to provide a better understanding of the neural basis of psychopathology and clinical features of these disorders, in order to raise new perspectives in every-day clinical practice.

Paolo Brambilla, Section Editor and Michele Tansella, Editor EPS