Articles/United States of America

Pittsburgh Registry of Infant Multiplets (PRIM)

Melissa Strassberg^a1, Katherine Peters^a2, Mary Marazita^a3, Jennifer Ganger^a4, Margaret Watt-Morse^a5, Lenn Murrelle^a6, Ralph Tarter^a7 and Michael Vanyukov^a8 c1

^a1 Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

^a2 Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

^a3 Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Cleft Palate-Craniofacial Center, School of Dental Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Department of Oral and Maxillofacial Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Center for Education and Drug Abuse Research (CEDAR), Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

^a4 Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

^a5 Magee-Womens Hospital, Pittsburgh, Pennsylvania, USA

^a6 Mid-Atlantic Twin Registry,Virginia Commonwealth University, Richmond,Virginia, USA

^a7 Center for Education and Drug Abuse Research (CEDAR), Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

^a8 Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Center for Education and Drug Abuse Research (CEDAR), Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USAmmv@pitt.edu

Abstract

This paper describes the Pittsburgh Registry of Infant Multiplets (PRIM; Pittsburgh, Pennsylvania), the results of pilot research conducted in this registry, and the plans for future studies. The main focus of the registry is on psychological development and the risk for behavioral disorders. Particularly, characteristics associated with antisociality and the risk for substance use disorders (e.g., aggressivity, hyperactiv-ity/impulsivity), as well as language development and other traits (e.g., dental health) are among the research targets.

Correspondence:

^c1 Address for correspondence: Michael Vanyukov, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA.