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Self-generation Enhances Verbal Recall in Individuals Infected with HIV

Published online by Cambridge University Press:  12 October 2011

Erica Weber ,
Steven Paul Woods ,
Emily Kellogg ,
Igor Grant  and
Michael R. Basso
Erica Weber
Affiliation:
Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, California Joint Doctoral Program in Clinical Psychology, San Diego State University, University of California, San Diego, San Diego, California
Steven Paul Woods*
Affiliation:
Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, California
Emily Kellogg
Affiliation:
Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, California
Igor Grant
Affiliation:
Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, California
Michael R. Basso
Affiliation:
Department of Psychology, University of Tulsa, Tulsa, Oklahoma
*
Correspondence and reprint requests to: Steven Paul Woods, HIV Neurobehavioral Research Program, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, California 92103-8231. E-mail: spwoods@ucsd.edu
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Abstract

Despite the prevalence of HIV-associated episodic memory impairment and its adverse functional impact, there are no empirically validated cognitive rehabilitation strategies for HIV-infected persons. The present study examined the self-generation approach, which is theorized to enhance new learning by elaborating and deepening encoding. Participants included 54 HIV-infected and 46 seronegative individuals, who learned paired word associates in both self-generated and didactic encoding experimental conditions. Results revealed main effects of HIV serostatus and encoding condition, but no interaction. Planned comparisons showed that both groups recalled significantly more words learned in the self-generation condition, and that HIV+ individuals recalled fewer words overall compared to their seronegative counterparts at delayed recall. Importantly, HIV+ participants with clinical memory impairment evidenced similar benefits of self-generation compared to unimpaired HIV+ subjects. Self-generation strategies may improve verbal recall in individuals with HIV infection and may, therefore, be an appropriate and potentially effective cognitive rehabilitation tool in this population. (JINS, 2012, 18, 128–133)

Keywords

Episodic memoryNeuropsychological assessmentAIDS dementia complexGeneration effect (learning)CognitionCognitive rehabilitation
Type
Brief Communications
Information
Journal of the International Neuropsychological Society , Volume 18 , Issue 1 , January 2012 , pp. 128 - 133
Copyright
Copyright © The International Neuropsychological Society 2011

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