Cardiology in the Young

Part 1: A Holistic Approach to Hypoplastic Left Heart Syndrome

Neonatal surgical reconstruction and peri-operative care for hypoplastic left heart syndrome: current strategies

Stephanie Fullera1 c1, Nancy Ghanayema2, Paul Chaia3, John Nigroa4, Thomas Kleislia5 and Sarah Tabbutta6

a1 Cardiac Surgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

a2 Division of Pediatric Critical Care Medicine, Children's Hospital of Wisconsin and Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

a3 The Congenital Heart Institute of Florida (CHIF), All Children's Hospital, Saint Petersburg and Tampa, Florida, United States of America

a4 Cardiac Surgery, Phoenix Children's Hospital and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States of America

a5 Phoenix Children's Hospital and St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States of America

a6 Division of Pediatric Critical Care Medicine, Benioff Children's Hospital, University of California, San Francisco, United States of America

Abstract

The management of newborns with hypoplastic left heart syndrome has changed significantly over the past three decades, with an associated dramatic improvement in outcomes. The aim of this paper is to discuss current peri-operative and palliative surgical strategies. Owing to the fact that comparative outcomes for these strategies have been addressed in a limited number of prospective trials and extractions from multi-centred databases, the primary focus of this review is descriptive.

(Online publication December 13 2011)

Correspondence:

c1 Correspondence to: Dr Stephanie Fuller, MD, Cardiac Surgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America. Tel: 215-590-2708; Fax: 215-590-2715; E-mail: FULLERS@email.chop.edu