British Journal of Nutrition

Papers of direct relevance to Clinical and Human Nutrition

The induction of obesity in the rat with bipiperidyl mustard

S. A. Jagota1, G. P. Webba1, P. D. Rogersa1 and J. W. T. Dickersona2

a1 Department of Paramedical Sciences, North East London Polytechnic, Romford Road, London E15 4LZ

a2 Department of Biochemistry, University of Surrey, Guildford, Surrey G U2 5 XH


Bipiperidyl mustard produced increased adiposity in the rat without excessive weight gain or hyperphagia.

The results suggest a metabolic aetiology for the obesity as opposed to a disorder of food intake regulation.

(Received December 05 1979)

(Accepted June 03 1980)