Journal of the International Neuropsychological Society

Symposium

Late-Life Social Activity and Cognitive Decline in Old Age

Bryan D. Jamesa1a2 c1, Robert S. Wilsona1a3a4, Lisa L. Barnesa1a3a4 and David A. Bennetta1a3

a1 Rush Alzheimer's Disease Center, Chicago, Illinois

a2 Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois

a3 Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois

a4 Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois

Abstract

We examined the association of social activity with cognitive decline in 1138 persons without dementia at baseline with a mean age of 79.6 (SD = 7.5) who were followed for up to 12 years (mean = 5.2; SD = 2.8). Using mixed models adjusted for age, sex, education, race, social network size, depression, chronic conditions, disability, neuroticism, extraversion, cognitive activity, and physical activity, more social activity was associated with less cognitive decline during average follow-up of 5.2 years (SD = 2.7). A one point increase in social activity score (range = 1–4.2; mean = 2.6; SD = 0.6) was associated with a 47% decrease in the rate of decline in global cognitive function (p < .001). The rate of global cognitive decline was reduced by an average of 70% in persons who were frequently socially active (score = 3.33, 90th percentile) compared to persons who were infrequently socially active (score = 1.83, 10th percentile). This association was similar across five domains of cognitive function. Sensitivity analyses revealed that individuals with the lowest levels of cognition or with mild cognitive impairment at baseline did not drive this relationship. These results confirm that more socially active older adults experience less cognitive decline in old age. (JINS, 2011, 17, 998–1005)

(Received December 02 2010)

(Revised March 11 2011)

(Accepted March 11 2011)

Keywords

  • *Cognition;
  • Cognitive reserve;
  • *Aging;
  • Social behavior;
  • *Life Style;
  • Risk reduction behavior;
  • Longitudinal studies;
  • Epidemiology

Correspondence:

c1 Correspondence and reprint requests to: Bryan D. James, Rush Alzheimer’ Disease Center, Room 1038, 600 South Paulina Street, Chicago, IL 60612. E-mail: bryan_james@rush.edu

Footnotes

* For special anniversary issue of the Journal of the International Neuropsychological Society, “The impact of Activity on Cognitive Health Across the Life Span”.