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Parasitology

Table of Contents - 2001 - Volume 122, Issue 05  


Parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) genetic diversity: population structure in a fragmented landscape

C.  SIRE  a1, J.  LANGAND  a1, V.  BARRAL  a1 and A.  THÉRON  a1 c1
a1 Laboratoire de Biologie Animale, UMR CNRS-UP 5555, Centre de Biologie et d'Ecologie Tropicale et Méditerranéenne, Université, 52 Av. de Villeneuve, 66860 Perpignan Cedex, France

Article author query
sire c   [PubMed][Google Scholar] 
langand j   [PubMed][Google Scholar] 
barral v   [PubMed][Google Scholar] 
theron a   [PubMed][Google Scholar] 

Abstract

Random amplified polymorphic DNA (RAPD) markers were used to quantify genetic diversity within and between 5 populations of Schistosoma mansoni within its definitive host (Rattus rattus) and the 5 corresponding populations of the snail intermediate host (Biomphalaria glabrata) from a limited endemic area of murine schistosomiasis on the island of Guadeloupe. Analysis of molecular variance (AMOVA) and canonical correspondence analysis (CCA) were used to test the significance of genetic differentiation between populations. Both methods gave similar results. Of total gene diversity, 15.1% (AMOVA) and 18.8% (CCA) was partitioned between localities for S. mansoni with an absence of association between genetic and geographical distances. Geographical localities accounted for 20.5% (CCA) of the total diversity for B. glabrata populations. The genetic distances between pairs of parasite populations were not correlated with the genetic distances between the corresponding pairs of snail host populations. Such strong patterns of local differentiation of both parasite and snail populations are consistent with predictions based on metapopulation dynamics and may have implications on host–parasite susceptibility relationship through local adaptation processes.

(Received October 20 2000)
(Revised November 24 2000)
(Accepted November 30 2000)


Key Words: Schistosoma mansoni; Biomphalaria glabrata; genetic population structure; RAPDs.

Correspondence:
c1 Corresponding author. Tel: +33 4 68 66 21 83. Fax: +33 4 68 66 22 81. E-mail: theron@univ-perp.fr

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