Genetics Research

Research Papers

Genomic selection in livestock populations

MICHAEL E. GODDARDa1a2 c1, BEN J. HAYESa2 and THEO H. E. MEUWISSENa3

a1 Department of Agriculture and Food Systems, University of Melbourne, Parkville 3010, Australia

a2 Victorian Department of Primary Industries, 1 Park Drive, Bundoora, Australia

a3 University of Life Sciences, P.O. Box 5003, 1432 Ås, Norway

Summary

Most traits of economic importance in livestock are either quantitative or complex. Despite considerable efforts, there has been only limited success in identifying the polymorphisms that cause variation in these traits. Nevertheless, selection based on estimated breeding values (BVs), calculated from data on phenotypic performance and pedigree has been very successful. Genomic tools, such as single nucleotide polymorphism (SNP) chips, have led to a new method of selection called ‘genomic selection’ in which dense SNP genotypes covering the genome are used to predict the BV. In this review we consider the statistical methodology for estimating BVs from SNP data, factors affecting the accuracy, the long-term response to genomic selection and the design of breeding programmes including the management of inbreeding.

(Received October 13 2010)

(Revised November 17 2010)

(Online publication March 23 2011)

Correspondence:

c1 Corresponding author: Department of Agriculture and Food Systems, University of Melbourne, Parkville 3010, Australia. e-mail: mike.goddard@dpi.viv.gov.au

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