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The relationship among Mental Health Status (GHQ-12), Health Related Quality of Life (EQ-5D) and Health-State Utilities in a general population

Published online by Cambridge University Press:  11 April 2011

Pedro Serrano-Aguilar ,
Yolanda Ramallo-Fariña ,
Maria Del Mar Trujillo-Martín ,
Sergio Raul Muñoz-Navarro ,
Lilisbeth Perestelo-Perez  and
Carlos De Las Cuevas-Castresana
Pedro Serrano-Aguilar
Affiliation:
Planning & Evaluation Unit, Canary Islands Health Service, Santa Cruz de Tenerife (Spain) CIBER Epidemiología y Salud Pública (CIBERESP) (Spain)
Yolanda Ramallo-Fariña
Affiliation:
CIBER Epidemiología y Salud Pública (CIBERESP) (Spain) Canary Islands Foundation for Research & Health (Fundación Canaria de Investigación y Salud – FUNCIS) Santa Cruz de Tenerife (Spain)
Maria Del Mar Trujillo-Martín*
Affiliation:
Canary Islands Foundation for Research & Health (Fundación Canaria de Investigación y Salud – FUNCIS) Santa Cruz de Tenerife (Spain)
Sergio Raul Muñoz-Navarro
Affiliation:
School of Medicine, University of La Frontera, Temuco (Chile)
Lilisbeth Perestelo-Perez
Affiliation:
Planning & Evaluation Unit, Canary Islands Health Service, Santa Cruz de Tenerife (Spain) CIBER Epidemiología y Salud Pública (CIBERESP) (Spain)
Carlos De Las Cuevas-Castresana
Affiliation:
CIBER Epidemiología y Salud Pública (CIBERESP) (Spain) Department of Psychiatry, University of La Laguna, Canary Island (Spain)
*
Address for correspondence: Dr. Ma del Mar Trujillo Martìn, Servicio Canario de la Salud. Pérez de Rozas 5, 4°. 38004 Santa Cruz de Tenerife (Spain). Fax: +34-922-475751 E-mail: matrumar@gobiernodecanarias.org
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Summary

Aim – To assess the relationship between mental health and health-related quality of life (HRQL) in the general population, and to map GHQ-12 as a screening test for population psychological distress to a generic health state measure (EQ-5D) in order to estimate health state values and allow deriving quality-adjusted life years. Methods – Relationship between mental health and HRQL was examined from the 2004 Canary Islands’ Health Survey. Participants were classified as probable psychiatric cases according to GHQ-12. HRQL was measured by the EQ-5D index. Multivariate lineal regression analysis was used to examine the association between mental health and HRQL adjusting by socio-demographic variables and comorbidities. A multivariate regression model was built from EQ-5D to estimate health states values using GHQ-12 as exposure. Results – EQ-5D index scores decreased as the GHQ-12 scores increased. Clinical and socio-demographic factors influenced HRQL without changing the overall trend for this negative relationship. The regression equation explained 43% of the variance. For estimation of utility scores, the model showed a high predictive capacity, with a mean forecast errors of 16%. Conclusions – HRQL progressively decreased when the probability of being a psychiatric case increased. Findings enable health state values to be derived from GHQ-12 scores for populations where utilities has not or cannot be measured directly.

Declaration of Interest: Authors declare no conflicts of interest. This work was supported by the Quality Plan for the National Health Service (Spanish Ministry of Health and Social Policy).

Keywords

Health surveysmental healthquality of lifequality-adjusted life years
Type
Original Articles
Information
Epidemiology and Psychiatric Sciences , Volume 18 , Issue 3 , September 2009 , pp. 229 - 239
Copyright
Copyright © Cambridge University Press 2009

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