Epidemiology and Infection

Rabies

Genetic evidence for domestic raccoon dog rabies caused by Arctic-like rabies virus in Inner Mongolia, China

X. Q. SHAOa1, X. J. YANa1 c2, G. L. LUOa1, H. L. ZHANGa1, X. L. CHAIa1, F. X. WANGa1, J. K. WANGa1, J. J. ZHAOa1, W. WUa1, S. P. CHENGa1, F. H. YANGa1, X. C. QINa2 and Y. Z. ZHANGa2 c1

a1 Divison of Zoonoses, Institute of Special Wild Economic Animal and Plant Science, CAAS, Jilin, China

a2 State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

SUMMARY

An outbreak of rabies affected domestic raccoon dogs on an animal farm in Inner Mongolia, China in 2007. A study was conducted to characterize the aetiological agent and clarify the origin of the rabies virus. Brain tissues were obtained from five rabid raccoon dogs. Viral nucleoprotein antigen was detected in the brain tissues and five rabies viruses were isolated from these rabid animals. Phylogenetic analysis of the N and G gene sequences showed that these isolates were closely related to Arctic-like rabies viruses isolated from the far-eastern region of Russia and South Korea, but distinct from the rabies viruses that are widely distributed in endemic areas in China. Epidemiological data suggested that the likely source of infection was from one wild raccoon dog that was captured and placed in the same type of pen used for domestic raccoon dogs.

(Accepted May 05 2010)

(Online publication June 14 2010)

Correspondence:

c1 Author for correspondence: Dr Yong-Zhen Zhang, State Key Laboratory for Infectious Disease Prevention and Control, Department of Zoonoses, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Liuzi 5, 102206, Beijing, China. (Email: yongzhenzhang@sohu.com) [Y. Z. Zhang]

c2 (Email: yanxijungmp@163.com) [X. J. Yan]

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