Proceedings of the Nutrition Society

Cambridge Journals Online - CUP Full-Text Page

Meeting Report

Recent advances in the physiology of eating


Stephen Frencha1 c1 and Kate Castiglionea2



a1 Masterfoods (a division of Mars UK Ltd), Dundee Road, Slough SL1 4JX, UK

a2 Centre for Human Nutrition, University of Sheffield, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK

Article author query

French S [PubMed]  [Google Scholar]
Castiglione K [PubMed]  [Google Scholar]

Abstract

Since the discovery of the protein product of the ob/ob gene, leptin, knowledge of the neurochemical pathways involved in the regulation of feeding has increased enormously. Our understanding of the mechanisms regulating food intake in man has also progressed greatly over a similar time span. Previous research into the regulation of food intake has largely proceeded through a reductionist approach, defining ever-smaller components of these mechanisms. This research strategy has been very productive and instructive, and has yielded a great deal of information on the specific putative components linking energy status and food intake. However, to fully understand the regulation of feeding it is important that these components are systematically reconstructed to investigate relevant interactions. In the present review recent data relating to interactions between systems proposed to be involved in feeding regulation will be highlighted. The review will be directed predominantly (but not exclusively) towards the regulation of human feeding.

Key Words: Feeding behaviour; Physiology of eating; Man

Correspondence:

c1 *Corresponding author: Dr Stephen French, fax +44 1753 514499, email Stephen.French@eu.effem.com