Sudan: the possible original focus of visceral leishmaniasis
Fifty-two Leishmania strains, obtained from human patients and dogs in a visceral leishmaniasis focus in Sudan, were characterized by isoenzyme electrophoresis (15 enzymes). The phylogenetic analysis showed that the 7 Leishmania zymodemes obtained hold ancestral positions on the phylogenetic tree, supporting the hypothesis of an East African origin of visceral leishmaniasis.(Received August 11 2000)
(Revised January 12 2000)
(Accepted January 14 2000)
Key Words: Leishmania; systematics; phylogeny; Leishmania donovani; Leishmania archibaldi; Leishmania infantum; Sudan.
c1 Corresponding author: Laboratoire de Parasitologie, 163 rue Auguste-Broussonet, 34090 Montpellier, France. Tel: +334 67 63 27 51. Fax: +334 67 63 00 49. E-mail: email@example.com