a1 Department of Epidemiology and Biostatistics, School of Public Health and Family Medicine, Capital Medical University, Beijing, China
a2 STD and AIDS Clinical Center, Beijing Youan Hospital, Capital Medical University, Beijing, China
a3 National Center for AIDS/STD Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing, China
To evaluate the prevalence of hepatitis C virus (HCV) and/or hepatitis B virus (HBV) infections in HIV-infected patients in China, an epidemiological serosurvey was conducted from May 2007 to September 2008 using a random cluster sampling design of infectious disease hospitals in seven high HIV-prevalent provinces (municipalities). Univariate analysis and logistic regression were used to study the determinants of HIV and HBV and/or HCV co-infection. The overall prevalence was 41·83% (95% CI 40·36–43·30) for anti-HCV and 12·49% (95% CI 11·50–13·48) for HBsAg, respectively. The prevalence of anti-HCV and HBsAg varied according to the route of HIV transmission. Compared to those with sexually acquired HIV infection, intravenous drug users and blood donors/recipients had the greatest risk of carrying anti-HCV. Needle sharing and unprotected sexual exposures are important modes of transmission for HBV. Further interventions including health education and harm reduction strategies should be implemented in high-risk populations.
(Accepted June 03 2010)
(Online publication July 02 2010)
c1 Author for correspondence: Dr Hao Wu, STD and AIDS Clinical Center, Beijing Youan Hospital, Capital Medical University, No. 8 Xitoutiao, You An Men, Beijing 100069, P.R. China. (Email: email@example.com)
† These authors contributed equally to this work.