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Superparamagnetic Iron Oxide Nanoarticles for Biomedical Applications: a focus on PVA as a coating

Published online by Cambridge University Press:  01 February 2011

M. Chastellain
Affiliation:
Powder Technology Laboratory, Swiss Federal Institute of Technology (EPFL), Switzerland
A. Petri
Affiliation:
Powder Technology Laboratory, Swiss Federal Institute of Technology (EPFL), Switzerland
H. Hofmann
Affiliation:
Powder Technology Laboratory, Swiss Federal Institute of Technology (EPFL), Switzerland
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Abstract

Nanoscaled particles showing a superparamagnetic behavior have been intensively studied these past years for biomedical applications and water-based ferrofluids turned out to be promising candidates for various in vivo as well as in vitro applications. Nevertheless, the lack of well-defined particles remains an important problem. One of the major challenges is still the large-scale synthesis of particles with a narrow size distribution. In this work iron oxide nanoparticles are obtained by classical co-precipitation in a water-based medium and are subsequently coated with polyvinyl alcohol. The thus obtained ferrofluids are studied and a focus is made on their colloidal stability.

Type
Research Article
Copyright
Copyright © Materials Research Society 2004

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References

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