Epidemiology and Infection

Sepsis

An outbreak of neonatal sepsis presenting with exanthematous rash caused by Klebsiella pneumoniae

R. VISWANATHANa1 c1, A. K. SINGHa1, S. MUKHERJEEa1, R. MUKHERJEEa1, P. DASa2 and S. BASUa2

a1 Department of Neonatology, Institute of Post Graduate Medical Education and Research, Kolkata, India

a2 National Institute of Cholera and Enteric Disease, Kolkata, India

SUMMARY

Newborns often present with skin conditions ranging from transient benign to severe. An occasional cause of neonatal exanthemic rash is infection due to Gram-positive bacteria, but Gram-negative infection is uncommon. We describe an outbreak of sepsis in 10 neonates over a 2-week period, caused by Klebsiella pneumoniae in a level III neonatal intensive care unit (NICU). Seven babies developed an exanthematous maculopapular rash. Molecular analysis by pulsed-field gel electrophoresis showed that all the babies with rash were infected by a single strain of K. pneumoniae which was distinct from the strain recovered from babies without rash.

(Accepted March 09 2010)

(Online publication April 07 2010)

Correspondence:

c1 Author for correspondence: Dr R. Viswanathan, Flat no. 2C, AMBIKA, 306, P. Mazumdar Road, Kolkata 700078, India. (Email: rupa_vish@rediffmail.com)

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